Evidence map›Paper›PMID 20113556›Full record

ArticleEmerging infectious diseases2010

Tropheryma whipplei in patients with pneumonia.

Sabri Bousbia, Laurent Papazian, Jean Pierre Auffray, Florence Fenollar, Claude Martin, Wenjun Li, Laurent Chiche, Bernard La Scola, Didier Raoult

Open access · diamondAbstract readMulticenter Study
In one paragraph

Article in Emerging infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 107 citations in OpenAlex.

  1. Diagnostics (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Deciphering whipple's disease complexity.Clinical and experimental medicine · 2026
    Review
  4. Article
  5. Frontiers in medicine · 2026
    Article
  6. Review
  7. Severe and Rapid Progression ofRespirology case reports · 2025
    Article
  8. Diagnosis ofFrontiers in medicine · 2025
    Article
  9. Article
  10. Respiratory medicine case reports · 2025
    Article
  11. Clinical Features of Patients withInfection and drug resistance · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Co-infection ofWorld journal of clinical cases · 2023
    Article
  18. Article
  19. An unusual case of severe pneumonia caused byWorld journal of emergency medicine · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sabri BousbiaCNRS-IRD Faculte de Medecine, Marseille, France.
Laurent Papazian
Jean Pierre Auffray
Florence Fenollar
Claude Martin
Wenjun Li
Laurent Chiche
Bernard La Scola
Didier Raoult
Institut de Recherche pour le Développement · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tropheryma whipplei is the etiologic pathogenic agent of Whipple disease (WD), characterized by various clinical signs, such as diarrhea, weight loss, lymphadenopathy, and polyarthritis. PCR-based methods for diagnosis of WD have been developed. T. whipplei has been identified in saliva and stool samples from patients with WD and from healthy persons. T. whipplei DNA has also been found in bronchoalveolar lavage (BAL) samples of a child with pneumonia. We detected DNA of T. whipplei in 6 (3%) of 210 BAL samples collected in intensive care units by using 16S rDNA and specific quantitative PCR. We identified 4 novel genotypes of T. whipplei. In 1 case, T. whipplei was the only bacterium; in 4 others, it was associated with buccal flora. We suggest that T. whipplei should be investigated as an etiologic agent of pneumonia.

Indexed as

Actinomycetales InfectionsAdolescentAdultAgedAged, 80 and overBronchoalveolar Lavage FluidCommunity-Acquired InfectionsHumansIntensive Care UnitsMaleMiddle AgedPneumonia, BacterialPolymerase Chain ReactionPopulation SurveillanceSalivaTropheryma

Identifiers

PMID20113556
PMCPMC2957999
OpenAlexW2140038914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.