Evidence map›Paper›PMID 20112968›Full record

ArticleACS nano2010

Host-guest interaction mediated polymeric assemblies: multifunctional nanoparticles for drug and gene delivery.

Jianxiang Zhang, Hongli Sun, Peter X Ma

Abstract read
In one paragraph

Article in ACS nano, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Nanoparticles in Cancer Diagnosis and Treatment.Materials (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Biosafe nanoscale pharmaceutical adjuvant materials.Journal of biomedical nanotechnology · 2014
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jianxiang ZhangDepartment of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI 48109, USA.
Hongli Sun
Peter X Ma

Funding

Periodontal Engineering Using Biomimetic Nano ScaffoldsR01DE015384 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MA, PETER X · 2003 to 2011
$2.9M
Orchestrating Bone Regeneration on Multiple ScalesR01DE017689 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MA, PETER X · 2007 to 2010
$1.4M
NIDCR NIH HHS DE015384NIDCR NIH HHS DE017689NIDCR NIH HHS R01 DE015384NIDCR NIH HHS R01 DE017689
6 · The paper itself

Abstract

Novel core-shell structured nanoassemblies are assembled by a beta-cyclodextrin containing a positively charged host polymer and a hydrophobic guest polymer. The hydrophobic core of these types of assemblies serves as a nanocontainer to load and release the hydrophobic drugs, while the positively charged hydrophilic shell is able to condense the plasmid DNA and achieve its transfection/expression in osteoblast cells. These assemblies may be used as a new generation of multifunctional nanocarriers for simultaneous drug delivery and gene therapy.

Indexed as

Gene Transfer TechniquesAnimalsbeta-CyclodextrinsCell LineDexamethasoneDNADrug CarriersHydrophobic and Hydrophilic InteractionsModels, MolecularMolecular ConformationNanoparticlesOsteoblastsParticle SizePeptidesPolyethyleneiminePolymersbeta-CyclodextrinsDexamethasoneDNADrug CarriersPeptidespoly-beta-benzyl-aspartatePolyethyleneiminePolymers

Identifiers

PMID20112968
PMCPMC2835570

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.