ArticleThe journal of headache and pain2010
Comorbidity between headache and epilepsy in a pediatric headache center.
Article in The journal of headache and pain, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 92 citations in OpenAlex.
- Global, regional, and national children and adolescent epilepsy burden, 1990-2021: an analysis based on the global burden of disease study 2021.Annals of medicine · 2025Article
- Epilepsy and migraine: a diagnostic and therapeutic challenge.Frontiers in pharmacology · 2025Review
- Exploring the symptoms and sleep disorders associated with migraines in women of Syria: A cross-sectional observational study.Health science reports · 2024Article
- Primary Headache Is Related to Reduced Health-Related Quality of Life in Children with Epilepsy.Healthcare (Basel, Switzerland) · 2024Article
- Migraine - a borderland disease to epilepsy: near it but not of it.The journal of headache and pain · 2024Review
- A Narrative Review of Visual Hallucinations in Migraine and Epilepsy: Similarities and Differences in Children and Adolescents.Brain sciences · 2023Review
- Visual Disturbances Spectrum in Pediatric Migraine.Journal of clinical medicine · 2023Review
- The broad-spectrum activity of perampanel: state of the art and future perspective of AMPA antagonism beyond epilepsy.Frontiers in neurology · 2023Review
- Mechanism of stress-induced attacks in an episodic neurologic disorder.Science advances · 2022Article
- Pathophysiological Bases of Comorbidity in Migraine.Frontiers in human neuroscience · 2021Review
- The comorbidity of headaches in pediatric epilepsy patients: How common and what types?Neurosciences (Riyadh, Saudi Arabia) · 2019Article
- [Pain and epilepsy : A clinical, neuroanatomical and pathophysiological review].Schmerz (Berlin, Germany) · 2018Article
- Secondary Headaches in Children and Adolescents: What Not to Miss.Current neurology and neuroscience reports · 2018Review
- A systematic approach for identifying shared mechanisms in epilepsy and its comorbidities.Database : the journal of biological databases and curation · 2018Article
- Factors Associated with Favorable Outcome of Topiramate Migraine Prophylaxis in Pediatric Patients.Journal of clinical neurology (Seoul, Korea) · 2017Article
- Headache and Epilepsy.Journal of epilepsy research · 2017Review
- The genetic relationship between epilepsy and hemiplegic migraine.Neuropsychiatric disease and treatment · 2017Review
- Diagnosis and Treatment of Childhood Migraine.Current treatment options in neurology · 2016Review
- Association of Migraine and Sleep-Related Breathing Disorder: A Population-Based Cohort Study.Medicine · 2015Observational
- Headache in epilepsy: prevalence and clinical features.The journal of headache and pain · 2015Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to analyse the comorbidity between headache and epilepsy in a large series of children with headache (1,795). Fifty-six cases (3.1%) suffered from idiopathic headache and idiopathic or cryptogenic epilepsy or unprovoked seizures. There was a strong association between migraine and epilepsy: in migraineurs (46/56) the risk of epilepsy was 3.2 times higher when compared with tension-type headache, without significant difference between migraine with and without aura (P = 0.89); children with epilepsy had a 4.5-fold increased risk of developing migraine than tension-type headache. In cases with comorbidity, focal epilepsies prevailed (43/56, 76.8%). Migraineurs affected by focal epilepsies (36/56) had a three times higher risk of having a cryptogenic epilepsy (27/36, 75%) than an idiopathic epilepsy (9/36, 25%) (P = 0.003). In migraine with aura, epilepsy preceded migraine in 71% of cases. Photosensitivity (7/56, 12.5%) and positive family history for epilepsy (22/56, 39%) were frequent in cases with comorbidity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.