Evidence map›Paper›PMID 20111975›Full record

ArticleClinical rheumatology2010

The synergistic efficacy of adalimumab and pamidronate in a patient with ankylosing spondylitis.

Gleb Slobodin, Itzhak Rosner, Doron Rimar, Nina Boulman, Michael Rozenbaum, Majed Odeh

Registry-linked trialAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02313727 (Combined Treatment With TNF), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02313727 phase4unknown statusnot on this mapstarted 2014, after this paper: background citation

Combined Treatment With TNF (Tumor Necrosis Factor) Inhibitor and Pamidronate in AS Patients: Effect on the Radiographic Progression

TypeinterventionalSponsorBnai Zion Medical CenterRan2014 to 2017Enrolled30ConditionsAnkylosing SpondylitisArmsPamidronate, Placebo (NaCl 0.9%)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gleb SlobodinDepartment of Internal Medicine A, Bnai Zion Medical Center, Ruth & Bruce Rappaport Faculty of Medicine, Technion, Haifa, 31048, PO Box 4940, Israel. gslobodin@yahoo.com
Itzhak Rosner
Doron Rimar
Nina Boulman
Michael Rozenbaum
Majed Odeh
Bnai Zion Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A patient with ankylosing spondylitis, after demonstrating incomplete clinical response to adalimumab, received three monthly infusions of pamidronate along with continuing TNF-alpha blockade. Complete disappearance of the back pain was reported after the second pamidronate infusion. The perspectives of the combination therapy with TNF-alpha inhibitor and pamidronate are discussed.

Indexed as

AdalimumabAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAnti-Inflammatory AgentsDiphosphonatesDrug SynergismDrug Therapy, CombinationFemaleHumansMiddle AgedPamidronateSpondylitis, AnkylosingTreatment OutcomeAdalimumabAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAnti-Inflammatory AgentsDiphosphonatesPamidronate

Identifiers

PMID20111975
OpenAlexW1976000009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.