ReviewNature2010
Towards building a chromosome segregation machine.
Review in Nature, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed.
- The role of active mRNA-ribosome dynamics and closing constriction in daughter chromosome separation inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Mechanism of spindle stability and poleward flux regulating spindle length during the metaphase.iScience · 2025Article
- Diffusion and distal linkages govern interchromosomal dynamics during meiotic prophase.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Machine learning classification of trajectories from molecular dynamics simulations of chromosome segregation.PloS one · 2022Article
- Mitotic chromosome condensation requires phosphorylation of the centromeric protein KNL-2 in C. elegans.Journal of cell science · 2021Article
- Spo0J and SMC are required for normal chromosome segregation in Staphylococcus aureus.MicrobiologyOpen · 2020Article
- Genome Segregation by the Venus Flytrap Mechanism: Probing the Interaction Between the ParF ATPase and the ParG Centromere Binding Protein.Frontiers in molecular biosciences · 2020Article
- Helical Twist and Rotational Forces in the Mitotic Spindle.Biomolecules · 2019Review
- Aurora A Protein Kinase: To the Centrosome and Beyond.Biomolecules · 2019Review
- Mitotic spindle: kinetochore fibers hold on tight to interpolar bundles.European biophysics journal : EBJ · 2018Review
- Entropy gives rise to topologically associating domains.Nucleic acids research · 2016Article
- Getting to the heart of an unusual kinetochore.Open biology · 2016Article
- Molecular Anatomy of ParA-ParA and ParA-ParB Interactions during Plasmid Partitioning.The Journal of biological chemistry · 2015Article
- A prophage-encoded actin-like protein required for efficient viral DNA replication in bacteria.Nucleic acids research · 2015Article
- Chromosomal attachments set length and microtubule number in the Saccharomyces cerevisiae mitotic spindle.Molecular biology of the cell · 2014Article
- A novel transcriptional activator, tubX, is required for the stability of Bacillus sphaericus mosquitocidal plasmid pBsph.Journal of bacteriology · 2014Article
- Bending the rules: widefield microscopy and the Abbe limit of resolution.Journal of cellular physiology · 2014Review
- Review
- The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast.Genetics · 2013Article
- Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae.Molecular biology of the cell · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
All organisms, from bacteria to humans, face the daunting task of replicating, packaging and segregating up to two metres (about 6 x 10(9) base pairs) of DNA when each cell divides. This task is carried out up to a trillion times during the development of a human from a single fertilized cell. The strategy by which DNA is replicated is now well understood. But when it comes to packaging and segregating a genome, the mechanisms are only beginning to be understood and are often as variable as the organisms in which they are studied.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.