Trial reportAJNR. American journal of neuroradiology2010
Tract-specific and region of interest analysis of corticospinal tract integrity in subcortical ischemic stroke: reliability and correlation with motor function of affected lower extremity.
Trial report in AJNR. American journal of neuroradiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- Repetitive transcranial magnetic stimulation reduces nicotine dependence and potentially modulates white matter microstructure in smokers: a pilot study by diffusion spectrum imaging.Frontiers in neurology · 2025Article
- Beyond Diffusion Tensor MRI Methods for Improved Characterization of the Brain after Ischemic Stroke: A Review.AJNR. American journal of neuroradiology · 2022Review
- Age-related assessment of diffusion parameters in specific brain tracts correlated with cortical thinning.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Diffusion Tensor Imaging Biomarkers to Predict Motor Outcomes in Stroke: A Narrative Review.Frontiers in neurology · 2019Review
- Diffusion Tensor Imaging Evaluation of Neural Network Development in Patients Undergoing Therapeutic Repetitive Transcranial Magnetic Stimulation following Stroke.Neural plasticity · 2018Article
- Article
- A majority rule approach for region-of-interest-guided streamline fiber tractography.Brain imaging and behavior · 2016Article
- Comparing prognostic strength of acute corticospinal tract injury measured by a new diffusion tensor imaging based template approach versus common approaches.Journal of neuroscience methods · 2016Article
- Assessment of white matter microstructure in stroke patients using NODDI.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2014Article
- A template-based procedure for determining white matter integrity in the internal capsule early after stroke.NeuroImage. Clinical · 2014Article
- Microstructural integrity of cerebral fiber tracts in hereditary spastic paraparesis with SPG11 mutation.AJNR. American journal of neuroradiology · 2013Article
- A longitudinal study of hand motor recovery after sub-acute stroke: a study combined FMRI with diffusion tensor imaging.PloS one · 2013Article
- Article
- Assessing a standardised approach to measuring corticospinal integrity after stroke with DTI.NeuroImage. Clinical · 2013Article
- Gait improvement after treadmill training in ischemic stroke survivors: A critical review of functional MRI studies.Neural regeneration research · 2012Article
- Establishing the reproducibility of two approaches to quantify white matter tract integrity in stroke.NeuroImage · 2012Article
- White matter reorganization and functional response after focal cerebral ischemia in the rat.PloS one · 2012Article
- Corticospinal tract integrity correlates with knee extensor weakness in chronic stroke survivors.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2011Article
- Diffusion tensor imaging and tractography of the corticospinal tract in the presence of enlarged Virchow-Robin spaces.Journal of neuroimaging : official journal of the American Society of NeuroimagingArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeTS analysis has been suggested as a useful method to evaluate the fiber integrity of white matter tracts. This study investigated the intrarater and interrater reliability and validity of a TS analysis for the CST and compared the results with those of a ROI-based analysis. MATERIALS AND
methodsDiffusion spectrum imaging was performed on 7 patients with subcortical ischemic stroke on a 3T MR imaging system. For the TS analysis, seed regions were placed at the cerebral peduncle and the medial portion of the primary motor cortex to reconstruct the tracts of the CST for motor control of the lower extremity. The mean GFA was measured at the PLIC by calculating the weighted sum of the GFAs sampled by the CST tracts at this segment. For the ROI-based analysis, the posterior two-thirds of the PLIC were enclosed on the GFA maps, and the mean GFA in this ROI was calculated.
resultsThe results showed good-to-excellent intrarater and interrater reliability on the seed region/ROI placement (mean kappa values >0.80) and mean GFA values (ICCs >0.90) for both the TS and ROI-based analyses. Both the GFA(PLIC-TS) and GFA(PLIC-ROI) values were highly correlated with the motor function of the affected lower extremity (r = 0.76 and 0.80, respectively; P < .05).
conclusionsWe demonstrated good reliability and validity of the TS and ROI-based analyses of the CST corresponding to lower extremity motor control in patients with subcortical ischemic stroke.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.