ArticleThe Journal of allergy and clinical immunology2010
Increased risk of serious pneumococcal disease in patients with atopic conditions other than asthma.
Article in The Journal of allergy and clinical immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Guideline
- Respiratory infections in adults with atopic disease and IgE antibodies to common aeroallergens.PloS one · 2013Pooled it
- Streptococcus pneumoniae colonisation in children and adolescents with asthma: impact of the heptavalent pneumococcal conjugate vaccine and evaluation of potential effect of thirteen-valent pneumococcal conjugate vaccine.BMC infectious diseases · 2016Trial
- Trial
- Atopic conditions other than asthma and risk of the 2009 novel H1N1 infection in children: a case-control study.Allergy and asthma proceedingsTrial
- Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors.International journal of dermatology · 2026Review
- A systematic review and meta-analysis of the correlation between cough variant asthma and mycoplasma pneumonia in children.Archives of medical science : AMS · 2024Review
- Risk of herpesvirus, serious and opportunistic infections in atopic dermatitis: a population-based cohort study.The British journal of dermatology · 2022Article
- Factors associated with IgG levels in adults with IgG subclass deficiency.BMC immunology · 2021Article
- Association between nasal and nasopharyngeal bacterial colonization in early life and eczema phenotypes.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021Article
- [Value of absolute counts of lymphocyte subsets in the early prediction of refractory Mycoplasma pneumoniae pneumonia in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019Article
- Longitudinal Associations Between Respiratory Infections and Asthma in Young Children.American journal of epidemiology · 2018Article
- Review
- Adult Atopic Dermatitis with Comorbid Atopic Disease is Associated with Increased Risk of Infections: A Population-Based Cross-Sectional Study.Dermatology and therapy · 2017Article
- IgE sensitization to inhalant allergens and the risk of airway infection and disease: A population-based study.PloS one · 2017Article
- Allergic Lung Inflammation Reduces Tissue Invasion and Enhances Survival from Pulmonary Pneumococcal Infection in Mice, Which Correlates with Increased Expression of Transforming Growth Factor β1 and SiglecF(low) Alveolar Macrophages.Infection and immunity · 2015Article
- The association between asthma and invasive pneumococcal disease: a nationwide study in Korea.Journal of Korean medical science · 2015Article
- Risks for infection in patients with asthma (or other atopic conditions): is asthma more than a chronic airway disease?The Journal of allergy and clinical immunology · 2014Review
- What does tympanostomy tube placement in children teach us about the association between atopic conditions and otitis media?Current allergy and asthma reports · 2014Review
- Increased risk of refractory Mycoplasma pneumoniae pneumonia in children with atopic sensitization and asthma.Korean journal of pediatrics · 2014Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundWe reported an increased risk of serious pneumococcal disease (SPD) among patients with asthma. It is not known whether this is true for patients with other atopic conditions.
objectiveTo determine the relationship between atopic conditions other than asthma and SPD.
methodsThe study subjects were residents of Rochester, Minn, who developed SPD between 1964 and 1983 and their 2 sex-matched and age-matched controls. We used a population-based computer-linked medical diagnosis system to identify all individuals with potential SPD. All records were reviewed by using explicit predetermined criteria for SPD. All individuals with atopic conditions were identified by the physician diagnoses including atopic dermatitis or eczema, allergic rhinitis, and hay fever documented in medical records. The associations between these atopic conditions and SPD were assessed by using conditional logistic regression.
resultsA total of 3941 records were reviewed, and we identified 174 SPD cases. Of these 174 cases, 50.6% were male, and 94.3% were Caucasian. Twenty-six (14.9%) of the SPD cases and 29 (8.3%) of the controls had atopy. Atopic conditions other than asthma were associated with an increased risk of SPD (odds ratio, 2.13; 95% CI, 1.04-4.35; P = .04) after adjusting for smoking status, previous high-risk conditions for SPD, educational status, and ethnicity.
conclusionLike asthma, other atopic conditions, particularly atopic dermatitis, are associated with an increased risk of SPD. There may be a common immunogenetic mechanism underlying increased risk of SPD among individuals with either asthma or other atopic conditions. Our study findings need to be studied further.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.