ReviewAgeing research reviews2011
Comparative cellular biogerontology: primer and prospectus.
Review in Ageing research reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Inflammaging in domestic dogs: basal level concentrations of IL-6, IL-1β, and TNF-α in serum of healthy dogs of different body sizes and ages.Biogerontology · 2023Article
- Article
- New Perspectives on Avian Models for Studies of Basic Aging Processes.Biomedicines · 2021Review
- Longevity and life history coevolve with oxidative stress in birds.Functional ecology · 2019Article
- Report: NIA workshop on translating genetic variants associated with longevity into drug targets.GeroScience · 2018Article
- Cellular metabolism and oxidative stress as a possible determinant for longevity in small breed and large breed dogs.PloS one · 2018Article
- Heightened induction of proapoptotic signals in response to endoplasmic reticulum stress in primary fibroblasts from a mouse model of longevity.The Journal of biological chemistry · 2011Article
- Fibroblasts from long-lived bird species are resistant to multiple forms of stress.The Journal of experimental biology · 2011Article
- Resistance of skin fibroblasts to peroxide and UV damage predicts hearing loss in aging mice.Aging cell · 2011Article
- Enhanced protein repair and recycling are not correlated with longevity in 15 vertebrate endotherm species.Age (Dordrecht, Netherlands) · 2011Article
- Functional linkages for the pace of life, life-history, and environment in birds.Integrative and comparative biology · 2010Article
- Not just a cousin of the naked mole-rat: Damaraland mole-rats offer unique insights into biomedicine.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Most prior work on the biological basis of aging has focused on describing differences between young and old individuals but provided only limited insight into the mechanisms controlling the rate of aging. Natural selection has produced a goldmine of experimental material, in the form of species of differing aging rate, whose longevity can vary by 10-fold or more within mammalian orders, but these resources remain largely unexplored at the cellular level. In this review article we focus on one approach to comparative biogerontology: the strategy of evaluating the properties of cultured cells from organisms of varying lifespan and aging rate. In addition, we discuss problems associated with the analysis and interpretations of interspecific variation of cellular trait data among species with disparate longevity. Given the impressive array of 'natural experiments' in aging rate, overcoming the technical and conceptual obstacles confronting research in comparative cellular gerontology will be well worth the effort.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.