Evidence map›Paper›PMID 20109189›Full record

ReviewHealth and quality of life outcomes2010

A review of health utilities using the EQ-5D in studies of cardiovascular disease.

Matthew T D Dyer, Kimberley A Goldsmith, Linda S Sharples, Martin J Buxton

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Health and quality of life outcomes, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03035539 (Rehabilitation of Patients With Atrial Fibrillation), which is not on this map. Cited by 218 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
218citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03035539 nacompletednot on this mapstarted 2012, after this paper: background citation

Rehabilitation of Patients With Atrial Fibrillation

TypeinterventionalSponsorAalborg University HospitalRan2012 to 2014Enrolled58ConditionsAtrial FibrillationArmsCardiac rehabilitation, Standard treatment
3 · Its place in the literature

Who cites it

218 citing papers in PubMed, 16 syntheses or guidelines pooled it.

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  6. Psychometric properties of the EQ-5D-5L: a systematic review of the literature.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
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  10. A comprehensive catalogue of EQ-5D scores in chronic disease: results of a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
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  12. The quality of life in Chinese population with chronic non-communicable diseases according to EQ-5D-3L: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
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158 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew T D DyerHealth Economics Research Group, Brunel University, Uxbridge, UK. mdyer@cru.rcpsych.ac.uk
Kimberley A Goldsmith
Linda S Sharples
Martin J Buxton

Funding

Medical Research Council MC_U105232027
6 · The paper itself

Abstract

backgroundThe EQ-5D has been extensively used to assess patient utility in trials of new treatments within the cardiovascular field. The aims of this study were to review evidence of the validity and reliability of the EQ-5D, and to summarise utility scores based on the use of the EQ-5D in clinical trials and in studies of patients with cardiovascular disease.

methodsA structured literature search was conducted using keywords related to cardiovascular disease and EQ-5D. Original research studies of patients with cardiovascular disease that reported EQ-5D results and its measurement properties were included.

resultsOf 147 identified papers, 66 met the selection criteria, with 10 studies reporting evidence on validity or reliability and 60 reporting EQ-5D responses (VAS or self-classification). Mean EQ-5D index-based scores ranged from 0.24 (SD 0.39) to 0.90 (SD 0.16), while VAS scores ranged from 37 (SD 21) to 89 (no SD reported). Stratification of EQ-5D index scores by disease severity revealed that scores decreased from a mean of 0.78 (SD 0.18) to 0.51 (SD 0.21) for mild to severe disease in heart failure patients and from 0.80 (SD 0.05) to 0.45 (SD 0.22) for mild to severe disease in angina patients.

conclusionsThe published evidence generally supports the validity and reliability of the EQ-5D as an outcome measure within the cardiovascular area. This review provides utility estimates across a range of cardiovascular subgroups and treatments that may be useful for future modelling of utilities and QALYs in economic evaluations within the cardiovascular area.

Indexed as

Cardiovascular DiseasesPsychometricsQuality of LifeSurveys and QuestionnairesHumansReproducibility of Results

Identifiers

PMID20109189
PMCPMC2824714

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.