ArticlePharmacy world & science : PWS2010
Coping with changes in the Defined Daily Dose in a longitudinal drug consumption database.
Article in Pharmacy world & science : PWS, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
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- Evaluation of Adult Outpatient Antibiotics Use at Jimma Medical Center (with Defined Daily Doses for Usage Metrics).Infection and drug resistance · 2021Article
- Antibiotic consumption study in two hospitals in Asmara from 2014 to 2018 using WHO's defined daily dose (DDD) methodology.PloS one · 2020Article
- Reply to Charra et al.: Global longitudinal assessment of 2019 changes in defined daily doses.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
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- The use of corticosteroids in patients with COPD or asthma does not decrease lung squamous cell carcinoma.BMC pulmonary medicine · 2015Article
- Prescribing efficiency of proton pump inhibitors in China: influence and future directions.BMC health services research · 2015Observational
- Can authorities appreciably enhance the prescribing of oral generic risperidone to conserve resources? Findings from across Europe and their implications.BMC medicine · 2014Article
- Different initiatives across Europe to enhance losartan utilization post generics: impact and implications.Frontiers in pharmacology · 2014Article
- Potential to enhance the prescribing of generic drugs in patients with mental health problems in austria; implications for the future.Frontiers in pharmacology · 2012Article
- Use of Generics-A Critical Cost Containment Measure for All Healthcare Professionals in Europe?Pharmaceuticals (Basel, Switzerland) · 2010Review
- Policies to enhance prescribing efficiency in europe: findings and future implications.Frontiers in pharmacology · 2010Article
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5 authors.
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Abstract
objectiveTo illustrate the best approach to accurate representation of temporal evolution of drug consumption, when confronted with changes over time in the Defined Daily Dose (DDD) measurement unit.
methodAs an example, drug consumption (2001-2005) at the University Hospital Rijeka was expressed with the corresponding DDD in each year; and with the DDD value of the last year of the observation time window. By visual appraisal, results with both methods were compared with the graph of drug consumption trends expressed in physical units (mg, IU, etc.).
resultsOf 20 drugs for which the DDD value has changed in the 5 year period, 5 were used in Rijeka hospital: erythropoietin parenteral, budesonide nasal spray, repaglinide oral, amoxicillin with clavulanic acid parenteral, and fentanyl transdermal. Graphs for individual drugs with the year by year method showed artificial jerks in the years proceeding the year of DDD change. Representation of total hospital consumption did not differ notably with the two methods.
conclusionDrug consumption data should be calculated with the latest DDD value in the time window. The policy of the World Health Organisation to keep changes to the system of DDD to a minimum should be continued.
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