ReviewJournal of mammary gland biology and neoplasia2010
Gene expression in the third dimension: the ECM-nucleus connection.
Review in Journal of mammary gland biology and neoplasia, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 69 citations in OpenAlex.
- Invasin-functionalized PIC hydrogels enable long-term 3D culture of epithelial organoids.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Integrin-activatingProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Fatty acid synthase (FASN) signalome: A molecular guide for precision oncology.Molecular oncology · 2024Article
- Hi-BDiSCO: folding 3D mesoscale genome structures from Hi-C data using brownian dynamics.Nucleic acids research · 2024Article
- Studying Adipose Tissue in the Breast Tumor Microenvironment In Vitro: Progress and Opportunities.Tissue engineering and regenerative medicine · 2020Review
- Laparoscopic procedures impact on mast cell mediators, extracellular matrix and adhesion scoring system in rats.Annals of medicine and surgery (2012) · 2020Article
- The Vegetative Receptor-Vascular Reflex (VRVR) - A New Key to Regeneration.Frontiers in physiology · 2020Article
- Extracellular Matrix Degradation Products Downregulate Neoplastic Esophageal Cell Phenotype.Tissue engineering. Part A · 2019Article
- Complexity: the organizing principle at the interface of biological (dis)order.Journal of genetics · 2017Review
- EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth.Journal of hematology & oncology · 2017Article
- Impact of multicellular tumor spheroids as an in vivo‑like tumor model on anticancer drug response.International journal of oncology · 2016Article
- Penetration and intracellular uptake of poly(glycerol-adipate) nanoparticles into three-dimensional brain tumour cell culture models.Experimental biology and medicine (Maywood, N.J.) · 2016Article
- Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology.Trends in pharmacological sciences · 2016Review
- Maintenance of Hepatic Functions in Primary Human Hepatocytes Cultured on Xeno-Free and Chemical Defined Human Recombinant Laminins.PloS one · 2016Article
- The likely role of proteolytic enzymes in unwanted differentiation of stem cells in culture.Future science OA · 2015Review
- Fibronectin fibrillogenesis facilitates mechano-dependent cell spreading, force generation, and nuclear size in human embryonic fibroblasts.Integrative biology : quantitative biosciences from nano to macro · 2015Article
- Dynamic reciprocity between cells and their microenvironment in reproduction.Biology of reproduction · 2015Review
- Article
- The multiple facets of drug resistance: one history, different approaches.Journal of experimental & clinical cancer research : CR · 2014Review
- The wound healing, chronic fibrosis, and cancer progression triad.Physiological genomics · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Decades ago, we and others proposed that the dynamic interplay between a cell and its surrounding environment dictates cell phenotype and tissue structure. Whereas much has been discovered about the effects of extracellular matrix molecules on cell growth and tissue-specific gene expression, the nuclear mechanisms through which these molecules promote these physiological events remain unknown. Using mammary epithelial cells as a model, the purpose of this review is to discuss how the extracellular matrix influences nuclear structure and function in a three-dimensional context to promote epithelial morphogenesis and function in the mammary gland.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.