ReviewJournal of neurology, neurosurgery, and psychiatry1991
Extracranial metastases of medulloblastoma in adults: literature review.
Review in Journal of neurology, neurosurgery, and psychiatry, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 98 citations in OpenAlex.
- Hypercalcemia associated with relapsed medulloblastoma due to bone metastasis: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- The role of DNA methylation in directing treatment in medulloblastoma.Epigenomics · 2025Review
- A Rare Case of Bone Marrow Infiltration of Disseminated Medulloblastoma in a Young Adult.International journal of hematology-oncology and stem cell research · 2025Article
- Article
- Medulloblastoma with Subcutaneous Spread: A Rare Entity.Asian journal of neurosurgery · 2023Article
- Review
- New Developments in the Pathogenesis, Therapeutic Targeting, and Treatment of Pediatric Medulloblastoma.Cancers · 2022Review
- Tumor cells generate astrocyte-like cells that contribute to SHH-driven medulloblastoma relapse.The Journal of experimental medicine · 2021Article
- Review
- The molecular biology of medulloblastoma metastasis.Brain pathology (Zurich, Switzerland) · 2020Review
- Medulloblastoma in a 6 Year Old Mixed Breed Dog: Surgical Debulking and Chemotherapy.Frontiers in veterinary science · 2019Article
- Targeting mTOR as a Therapeutic Approach in Medulloblastoma.International journal of molecular sciences · 2018Review
- Bone Marrow Buffy Coat Cell Block for Confirmation of Isolated Bone Marrow Relapse in Medulloblastoma.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2017Article
- Medulloblastoma: Tumor Biology and Relevance to Treatment and Prognosis Paradigm.Current neurology and neuroscience reports · 2016Review
- Cervical lymph node metastases from remote primary tumor sites.Head & neck · 2016Review
- Subcutaneous metastasis in medulloblastoma: A case report and review of literature.Journal of pediatric neurosciences · 2013Article
- A survey of metastatic central nervous system tumors to cervical lymph nodes.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2010Review
- Procarbazine, lomustine, vincristine combination may be effective in adult medulloblastoma patients with systemic metastases.Journal of neuro-oncology · 2005Article
- Article
- Fabrication and testing of a device capable of reducing the incidence of ventricular shunt promoted metastasis.Journal of neuro-oncology · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A consecutive series of 30 cases of extracranial medulloblastoma metastases in adults is analysed. The majority of the patients were males with a 3:1 male/female ratio. Bone was the most frequent site of metastases in adults (77%) and children (78%), followed by lymph nodes (33%) in both children and adults. Lung metastases were more common in adults (17%), but liver metastases occurred more frequently in children (15%). Possible routes of spread and development of metastases are discussed, with special emphasis on the role of shunts in tumour seeding. Distant extracranial metastatic spread of medulloblastoma occurs at the rate of 7.1%. Mean interval between operation of the primary tumour and the discovery of metastases was shorter in children (20 months) than in adults (36 months). Survival after the discovery of metastases was also shorter in children (5 months) than in adults (9.5 months). Shunts were associated with an earlier appearance of metastases and with a poorer prognosis. A detailed review of the literature of 119 cases of medulloblastoma with extracranial metastases is provided.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.