ArticleJournal of neurophysiology2010
Receptive field mosaics of retinal ganglion cells are established without visual experience.
Article in Journal of neurophysiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed.
- Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa.Nature communications · 2023Article
- Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa.bioRxiv : the preprint server for biology · 2023Article
- Article
- Article
- Ignoring correlated activity causes a failure of retinal population codes.Nature communications · 2020Article
- New Features of Receptive Fields in Mouse Retina through Spike-triggered Covariance.Experimental neurobiology · 2020Article
- Electrical Imaging of Light-Induced Signals Across and Within Retinal Layers.Frontiers in neuroscience · 2020Article
- Expression of transcription factors divides retinal ganglion cells into distinct classes.The Journal of comparative neurology · 2019Article
- Pathway-Specific Asymmetries between ON and OFF Visual Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Neural architecture: from cells to circuits.Journal of neurophysiology · 2018Review
- Characterization of Retinal Functionality at Different Eccentricities in a Diurnal Rodent.Frontiers in cellular neuroscience · 2018Article
- Glutamate Activity Regulates and Dendritic Development of J-RGCs.Frontiers in cellular neuroscience · 2018Article
- Interlayer Repulsion of Retinal Ganglion Cell Mosaics Regulates Spatial Organization of Functional Maps in the Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Elevated IOP alters the space-time profiles in the center and surround of both ON and OFF RGCs in mouse.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Cell type-specific changes in retinal ganglion cell function induced by rod death and cone reorganization in rats.Journal of neurophysiology · 2017Article
- Transiency of retinal ganglion cell action potential responses determined by PSTH time constant.PloS one · 2017Article
- Synaptic Mechanisms Generating Orientation Selectivity in the ON Pathway of the Rabbit Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Frequency Responses of Rat Retinal Ganglion Cells.PloS one · 2016Article
- Photovoltaic restoration of sight with high visual acuity.Nature medicine · 2015Article
- A method for electrophysiological characterization of hamster retinal ganglion cells using a high-density CMOS microelectrode array.Frontiers in neuroscience · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
A characteristic feature of adult retina is mosaic organization: a spatial arrangement of cells of each morphological and functional type that produces uniform sampling of visual space. How the mosaics of visual receptive fields emerge in the retina during development is not fully understood. Here we use a large-scale multielectrode array to determine the mosaic organization of retinal ganglion cells (RGCs) in rats around the time of eye opening and in the adult. At the time of eye opening, we were able to reliably distinguish two types of ON RGCs and two types of OFF RGCs in rat retina based on their light response and intrinsic firing properties. Although the light responses of individual cells were not yet mature at this age, each of the identified functional RGC types formed a receptive field mosaic, where the spacing of the receptive field centers and the overlap of the receptive field extents were similar to those observed in the retinas of adult rats. These findings suggest that, although the light response properties of RGCs may need vision to reach full maturity, extensive visual experience is not required for individual RGC types to form a regular sensory map of visual space.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.