ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2010
Readiness discharge for spontaneous initiation of walking in crayfish.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- A brain-wide, trial- and time-dependent deterministic drive synergizes with within-trial noise to time self-initiated actions.bioRxiv : the preprint server for biology · 2026Article
- Slow ramping emerges from spontaneous fluctuations in spiking neural networks.Nature communications · 2024Article
- Article
- Ramp-to-threshold dynamics in a hindbrain population controls the timing of spontaneous saccades.Nature communications · 2021Article
- What Is the Readiness Potential?Trends in cognitive sciences · 2021Review
- Glutamatergic neurons of the gigantocellular reticular nucleus shape locomotor pattern and rhythm in the freely behaving mouse.PLoS biology · 2019Article
- Reckoning the moment of reckoning in spontaneous voluntary movement.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Free Will and Neuroscience: From Explaining Freedom Away to New Ways of Operationalizing and Measuring It.Frontiers in human neuroscience · 2016Article
- Free will and paranormal beliefs.Frontiers in psychology · 2014Article
- Designing and implementing nervous system simulations on LEGO robots.Journal of visualized experiments : JoVE · 2013Article
- Behavioral and neural signatures of readiness to initiate a learned motor sequence.Current biology : CB · 2013Article
- Neural basis of stimulus-angle-dependent motor control of wind-elicited walking behavior in the cricket Gryllus bimaculatus.PloS one · 2013Article
- An accumulator model for spontaneous neural activity prior to self-initiated movement.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Specialized brain regions and sensory inputs that control locomotion in leeches.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2012Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals initiate behavior not only reflexively but also spontaneously in the absence of external stimuli. In vertebrates, electrophysiological data on the neuronal activity associated with the self-initiated voluntary behavior have accumulated extensively. In invertebrates, however, little is known about the neuronal basis of the spontaneous initiation of behavior. We investigated the spike activity of brain neurons at the time of spontaneous initiation of walking in the crayfish Procambarus clarkii and found neuronal signals indicative of readiness or preparatory activities in the vertebrate brain that precede the onset of voluntary actions. Those readiness discharge neurons became active >1 s before the initiation of walking regardless of stepping direction. They remained inactive at the onset of mechanical stimulus-evoked walking in which other descending units were recruited. These results suggest that the parallel descending mechanisms from the brain separately subserve the spontaneous and stimulus-evoked walking. Electrical stimulation of these different classes of neurons caused different types of walking. In addition, we found other descending units that represented different aspects of walking, including those units that showed a sustained activity increase throughout the walking bout depending on its stepping direction, as well as one veto unit for canceling out the output effect of the readiness discharge and three termination units for stopping the walking behavior. These findings suggest that the descending activities are modularized in parallel for spontaneous initiation, continuation, and termination of walking, constituting a sequentially hierarchical control.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.