ArticleJournal of virology2010
Isolation of an infectious endogenous retrovirus in a proportion of live attenuated vaccines for pets.
Article in Journal of virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Pre-Cambrian origin ofeLife · 2026Article
- Gammaretrovirus Infections in Humans in the Past, Present, and Future: Have We Defeated the Pathogen?Pathogens (Basel, Switzerland) · 2026Review
- A genome-wide study of ruminants uncovers two endogenous retrovirus families recently active in goats.Mobile DNA · 2025Article
- Establishment of CRFK cells for vaccine production by inactivating endogenous retrovirus with TALEN technology.Scientific reports · 2022Article
- Vaccination as a Strategy to Prevent Bluetongue Virus Vertical Transmission.Pathogens (Basel, Switzerland) · 2021Review
- Transmission, Evolution, and Endogenization: Lessons Learned from Recent Retroviral Invasions.Microbiology and molecular biology reviews : MMBR · 2018Review
- Contamination of live attenuated vaccines with an infectious feline endogenous retrovirus (RD-114 virus).Archives of virology · 2014Review
- Complete genome sequences of two feline leukemia virus subgroup B isolates with novel recombination sites.Genome announcements · 2013Article
- A new approach to establish a cell line with reduced risk of endogenous retroviruses.PloS one · 2013Article
- Article
- Extraneous agent detection in vaccines--a review of technical aspects.Biologicals : journal of the International Association of Biological Standardization · 2012Review
- Viral and cellular requirements for the budding of feline endogenous retrovirus RD-114.Virology journal · 2011Article
- Article
- Development of a real-time reverse-transcription-PCR method for detection of RD114 virus in canine vaccines.Biologicals : journal of the International Association of Biological Standardization · 2011Article
- Experimental infection of dogs with a feline endogenous retrovirus RD-114.Acta veterinaria Scandinavica · 2011Article
- Phylogeny-directed search for murine leukemia virus-like retroviruses in vertebrate genomes and in patients suffering from myalgic encephalomyelitis/chronic fatigue syndrome and prostate cancer.Advances in virology · 2011Article
- Characterization of RD-114 virus isolated from a commercial canine vaccine manufactured using CRFK cells.Journal of clinical microbiology · 2010Article
- Of Mice and Men: On the Origin of XMRV.Frontiers in microbiology · 2010Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
The genomes of all animal species are colonized by endogenous retroviruses (ERVs). Although most ERVs have accumulated defects that render them incapable of replication, fully infectious ERVs have been identified in various mammals. In this study, we isolated a feline infectious ERV (RD-114) in a proportion of live attenuated vaccines for pets. Isolation of RD-114 was made in two independent laboratories using different detection strategies and using vaccines for both cats and dogs commercially available in Japan or the United Kingdom. This study shows that the methods currently employed to screen veterinary vaccines for retroviruses should be reevaluated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.