Evidence map›Paper›PMID 20105416›Full record

Trial reportJournal of studies on alcohol and drugs2010

Effects of pretreatment and posttreatment depressive symptoms on alcohol consumption following treatment in Project MATCH.

Stephanie A Gamble, Kenneth R Conner, Nancy L Talbot, Qin Yu, Xin M Tu, Gerard J Connors

Registry-linked trialOpen access · bronzeAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of studies on alcohol and drugs, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06366100 (Dissemination, Acceptability and Adaptation Study of Two Transdiagnostic Psychological Interventions Based on Emotional Regulation), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06366100 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Dissemination, Acceptability and Adaptation Study of Two Transdiagnostic Psychological Interventions Based on Emotional Regulation (ER) for the Treatment of Alcohol Addiction: Dialectical Behavioral Therapy(DBT) and Unified Protocol (UP)

TypeinterventionalSponsorUniversidad de ZaragozaRan2024 to 2025Enrolled160ConditionsImplementation ScienceArmsDialectical Behavior Therapy for Substance Use Disorder (DBT-SUD), Unified Protocol (UP)
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. The moderating effects of group cognitive-behavioral therapy for depression among substance users.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2012
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  15. Self-efficacy and social networks after treatment for alcohol or drug dependence and major depression: disentangling person and time-level effects.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stephanie A GambleDepartment of Psychiatry, School of Medicine and Dentistry, University of Rochester, 300 Crittenden Boulevard, Rochester, New York 14620, USA. stephanie_gamble@urmc.rochester.edu
Kenneth R Conner
Nancy L Talbot
Qin Yu
Xin M Tu
Gerard J Connors
University of Rochester · US

Funding

NIMH INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARDT32MH018911 · NIMH · UNIVERSITY OF ROCHESTER · PI CAINE, ERIC D. · 1988 to 2012
$2.9M
Attempted Suicide and Alcohol DependenceR01AA016149 · NIAAA · UNIVERSITY OF ROCHESTER · PI CONNER, KENNETH R · 2006 to 2009
$1.2M
Behavioral treatment for alcohol dependent women with co-occurring depressionK23AA017246 · NIAAA · UNIVERSITY OF ROCHESTER · PI GAMBLE, STEPHANIE A · 2008 to 2012
$690k
NIAAA NIH HHS K23 AA017246NIAAA NIH HHS K23AA017246NIAAA NIH HHS R01 AA016149NIAAA NIH HHS R01AA016149NIMH NIH HHS T32 MH018911NIMH NIH HHS T32MH18911
6 · The paper itself

Abstract

objectiveThis study examined the associations of pretreatment and posttreatment depressive symptoms with drinking outcomes in the year following treatment in Project MATCH (Matching Alcoholism Treatments to Client Heterogeneity), a multisite clinical trial of behavioral treatments for alcohol-use disorders.

methodData from 1,726 participants were modeled using generalized estimating equations to examine drinking frequency and intensity, as reflected by percentage days abstinent (PDA) and average drinks per drinking day (DDD). We predicted that patients who reported more pretreatment and posttreatment depressive symptoms would report greater drinking frequency (PDA) and more intense drinking (DDD) across the 12-month follow-up period.

resultsPretreatment Beck Depression Inventory (BDI) scores predicted more frequent and intense drinking in the year following treatment, although not after accounting for posttreatment BDI scores, which were associated with the drinking outcomes as hypothesized. Patients who reported more depressive symptoms in the year following treatment reported less abstinence (PDA) and more intense drinking (DDD) than patients with fewer posttreatment depressive symptoms.

conclusionsOur findings underscore the importance of obtaining repeated assessments of depression during the course of substance use treatment. Moreover, the data suggest the potential utility of augmenting standard chemical dependency care with depression-focused interventions for alcohol-dependent patients whose depressive symptoms do not subside during treatment.

Indexed as

AdultAlcohol DrinkingAlcohol-Related DisordersDepressionFemaleFollow-Up StudiesHumansMaleMiddle AgedTime FactorsTreatment Outcome

Identifiers

PMID20105416
PMCPMC2815065
OpenAlexW2171266323

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.