Evidence map›Paper›PMID 20105329›Full record

ArticleBMC microbiology2010

Genetic elements associated with antimicrobial resistance in enteropathogenic Escherichia coli (EPEC) from Brazil.

Isabel C A Scaletsky, Tamara B Souza, Katia R S Aranda, Iruka N Okeke

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 56 citations in OpenAlex.

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  12. Typical & atypical enteropathogenicThe Indian journal of medical research · 2017
    Article
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  17. Review
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  19. Clinical implications of enteroadherent Escherichia coli.Current gastroenterology reports · 2012
    Review
  20. Enteropathogenic escherichia coli infection in children.Current opinion in infectious diseases · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Isabel C A ScaletskyDepartamento de Microbiologia, Universidade Federal de São Paulo, Rua Botucatu 862, São Paulo 04023-062, Brazil. scaletsky@unifesp.br
Tamara B Souza
Katia R S Aranda
Iruka N Okeke
Universidade Federal de São Paulo · BRHaverford College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe recently observed an association of resistance with a certain enteropathogenic Escherichia coli (EPEC) serotypes and identified a conjugative plasmid, similar to plasmid pED208, that was conserved among archival O111:H2/NM and O119:H2 strains of diverse geographical origin. In this study, we sought to determine the prevalence and distribution of this plasmid among a collection of EPEC isolates from Brazil, as well as to study the susceptibilities of these isolates to antimicrobial agents.

resultsResistance was more commonly seen in typical EPEC than atypical strains. The most prevalent resistances were to ampicillin, tetracycline, streptomycin and the sulfonamides. Markers for the EPEC conjugative multiresistance plasmid, were detected in 21 (30%) of typical but only 4 (5%) of atypical strains (p = 0.001, Chi-squared test). This plasmid, previously reported from only O111 and O119 strains was found in O55 and O127 strains and was associated with the presence of class 1 integrons.

conclusionOur data suggest a limited but expanding host range for the EPEC resistance plasmid.

Indexed as

Anti-Bacterial AgentsBrazilChild, PreschoolChi-Square DistributionDrug Resistance, Multiple, BacterialEnteropathogenic Escherichia coliEscherichia coli InfectionsGenes, BacterialHumansMicrobial Sensitivity TestsPlasmidsPrevalenceAnti-Bacterial Agents

Identifiers

PMID20105329
PMCPMC2828443
OpenAlexW2063042391

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.