Evidence map›Paper›PMID 20104223›Full record

ReviewBritish journal of cancer2010

Treatment options for small cell lung cancer - do we have more choice?

M Puglisi, S Dolly, A Faria, J S Myerson, S Popat, M E R O'Brien

Registry-linked trialAbstract readEvaluation StudyReview
In one paragraph

Review in British journal of cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05092412 (A First-line Multi-center, Single-arm Exploratory Study Using Low-dose Radiotherapy), which is not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05092412 phase2active not recruitingnot on this mapstarted 2022, after this paper: background citation

A First-line Multi-center, Single-arm Exploratory Study Using Low-dose Radiotherapy (LDRT) Combined With Durvalumab (MEDI4736), Etoposide, and Cisplatin/Carboplatin for Patients With Extensive-stage Small Cell Lung Cancer

TypeinterventionalSponsorYou LuRan2022 to 2027Enrolled30ConditionsLung Cancer, Extensive-stage Small-cell Lung Cancer, DurvalumabArmsLow-dose radiotherapy, Durvalumab, Etoposide, and cisplatin/carboplatin
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Article
  10. Non-Coding RNAs as Key Regulators in Lung Cancer.International journal of molecular sciences · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. OncoTargets and therapy · 2021
    Article
  18. Review
  19. The prognostic role of circulating CD8Journal of translational medicine · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M PuglisiDepartment of Medicine, The Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK.
S Dolly
A Faria
J S Myerson
S Popat
M E R O'Brien

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small cell lung cancer (SCLC) is a significant health problem worldwide because of its high propensity for relapse. This review discusses existing and future therapies for the treatment of SCLC.

Indexed as

AnimalsAntineoplastic AgentsAntineoplastic ProtocolsBiomedical ResearchChoice BehaviorHumansLung NeoplasmsNeoplasm StagingPrognosisSmall Cell Lung CarcinomaAntineoplastic Agents

Identifiers

PMID20104223
PMCPMC2837580

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.