Evidence map›Paper›PMID 20103693›Full record

ArticleJournal of clinical pharmacology2010

Use of enantiomeric bupropion and hydroxybupropion to assess CYP2B6 activity in glomerular kidney diseases.

Melanie S Joy, Reginald F Frye, Kristi Stubbert, Kim R Brouwer, Ronald J Falk, Evan D Kharasch

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical pharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Chirality of antidepressive drugs: an overview of stereoselectivity.Asian biomedicine : research, reviews and news · 2022
    Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Melanie S JoySchool of Medicine, University of North Carolina at Chapel Hill, UNC Kidney Center and Division of Nephrology and Hypertension, CB 7155, 7005 Burnett Womack Building, Chapel Hill, NC 27599-7155, USA. melanie_joy@med.unc.edu
Reginald F Frye
Kristi Stubbert
Kim R Brouwer
Ronald J Falk
Evan D Kharasch
University of North Carolina at Chapel Hill · USWashington University in St. Louis · USUniversity of Florida · USUniversity of North Carolina Health Care · US

Funding

Zonisamide in Patients with Neuropathic Pain Associated with Diabetic NeuropathyM01RR000046 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOY, MELANIE S · 1985 to 2008
$38.5M
UNC Clinical and Translational Science AwardUL1TR000083 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2012 to 2013
$11.6M
OPIOIDS IN CANCER PAIN &DRUG ABUSE--OPTIMIZING THERAPYK24DA000417 · NIDA · WASHINGTON UNIVERSITY · PI KHARASCH, EVAN D. · 1999 to 2010
$1.4M
Pharmacokinetics &Genomics in Glomerular DiseasesK23DK064888 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOY, MELANIE S · 2004 to 2008
$609k
NCATS NIH HHS UL1 TR000083NCRR NIH HHS M01 RR000046NCRR NIH HHS RR00046NCRR NIH HHS U54RR024383NIDA NIH HHS K24 DA000417NIDA NIH HHS K24DA00417NIDDK NIH HHS K23 DK064888NIDDK NIH HHS K23DK64888
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAntidepressive Agents, Second-GenerationAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisAryl Hydrocarbon HydroxylasesBupropionChronic DiseaseCytochrome P-450 CYP2B6FemaleHumansLupus NephritisMaleMiddle AgedOxidoreductases, N-DemethylatingPhenotypeStereoisomerismAntidepressive Agents, Second-GenerationAryl Hydrocarbon HydroxylasesBupropionCYP2B6 protein, humanCytochrome P-450 CYP2B6Oxidoreductases, N-Demethylatingradafaxine

Identifiers

PMID20103693
PMCPMC3614080
OpenAlexW2002085768

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.