ArticleJournal of medical primatology2010
Alopecia in Rhesus macaques correlates with immunophenotypic alterations in dermal inflammatory infiltrates consistent with hypersensitivity etiology.
Article in Journal of medical primatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Customized Open Patch Allergen Testing in a Rhesus Macaque (Macaca mulatta).Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Effects of Seasonality and Pregnancy on Hair Loss and Regrowth in Rhesus Macaques.Animals : an open access journal from MDPI · 2024Article
- Effect of Pregnancy and Age on Alopecia in Adult Female Baboons (Journal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
- The Patterns and Causes of Dermatitis in Terrestrial and Semi-Aquatic Mammalian Wildlife.Animals : an open access journal from MDPI · 2021Review
- Effects of Pregnancy, Outdoor Access, and Antifungal Medication on Hair Loss in Breeding-age Female Pigtailed Macaques (Comparative medicine · 2019Article
- Social hair pulling in captive rhesus macaques (Macaca mulatta).American journal of primatology · 2017Article
- Fatty acid supplements improve hair coat condition in rhesus macaques.Journal of medical primatology · 2017Article
- Assessing significant (>30%) alopecia as a possible biomarker for stress in captive rhesus monkeys (Macaca mulatta).American journal of primatology · 2017Article
- The correlation between alopecia and temperament in rhesus macaques (Macaca mulatta) at four primate facilities.American journal of primatology · 2017Article
- Prior facility affects alopecia in adulthood for rhesus macaques.American journal of primatology · 2017Article
- Factors influencing alopecia and hair cortisol in rhesus macaques (Macaca mulatta).Journal of medical primatology · 2016Article
- Alopecia in Outdoor Group- and Corral-Housed Baboons (Papio hamadryas spp.).Journal of the American Association for Laboratory Animal Science : JAALAS · 2015Article
- A simple alopecia scoring system for use in colony management of laboratory-housed primates.Journal of medical primatology · 2014Article
- Hair loss and hypothalamic-pituitary-adrenocortical axis activity in captive rhesus macaques (Macaca mulatta).Journal of the American Association for Laboratory Animal Science : JAALAS · 2014Article
- Alopecia in three macaque species housed in a laboratory environment.American journal of primatology · 2014Article
- Hair loss and hair-pulling in rhesus macaques (Macaca mulatta).Journal of the American Association for Laboratory Animal Science : JAALAS · 2013Article
- Application of the diagnostic evaluation for alopecia in traditional veterinary species to laboratory rhesus macaques (Macaca mulatta).Journal of the American Association for Laboratory Animal Science : JAALAS · 2011Article
- Specific pathogen-free status alters immunophenotype in rhesus macaques: implications for the study of simian immunodeficiency virus.AIDS research and human retroviruses · 2011Article
- Psychogenic alopecia in rhesus macaques presenting as focally extensive alopecia of the distal limb.Comparative medicine · 2011Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAlthough alopecia is a commonly recognized problem affecting many captive Rhesus macaque colonies, there is no consensus as to the underlying etiology or appropriate course of management.
methodsWe performed skin biopsies to assess underlying pathology in alopecic Rhesus macaques and performed immunohistochemical and metachromatic staining of these biopsies to assess the cellular infiltrates.
resultsAlopecia is associated with superficial dermal perivascular mononuclear cell infiltrates and skin pathology consistent with chronic hypersensitivity dermatitis. The inflammation is primarily composed of CD4+ cells admixed with histiocytes and mast cells. Inflammation is correlated with degree of alopecia. Further analysis in different groups of macaques revealed that animals born outdoors or infected with lung mites had reduced dermal inflammatory cell infiltrates and a lower incidence of alopecia.
conclusionsThese findings support a hypothesis that an altered housing status resulting in decreased pathogen burden in Rhesus macaque colonies may contribute to dermal immunophenotypic alterations and subsequent development of dermatitis with resultant alopecia.
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