When do minority drug-resistant HIV-1 variants have a major clinical impact?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

5 citing papers in PubMed.

1. Short-course Combivir after single-dose nevirapine reduces but does not eliminate the emergence of nevirapine resistance in women.Antiviral therapy · 2012
   Trial
2. Reappearance of minority K103N HIV-1 variants after interruption of ART initiated during primary HIV-1 infection.PloS one · 2011
   Trial
3. Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.Antimicrobial agents and chemotherapy · 2012
   Article
4. Transmitted HIV resistance to first-line antiretroviral therapy in Lima, Peru.AIDS research and human retroviruses · 2012
   Article
5. Factors limiting the transmission of HIV mutations conferring drug resistance: fitness costs and genetic bottlenecks.Scientific reports · 2012
   Article

Corrections and comments

• Comment on
  Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure.2010
• Comment on
  Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment- experienced patients.2010

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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