ArticleIndian journal of dermatology2009
Photo-stimulatory effect of low energy helium-neon laser irradiation on excisional diabetic wound healing dynamics in Wistar rats.
Article in Indian journal of dermatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Effects and parameterization of low-level laser therapy in diabetic ulcers: an umbrella review of systematic reviews and meta-umbrella.Lasers in medical science · 2025Pooled it
- Dose-response and efficacy of 660-nanometer low-level laser therapy in healing diabetic foot ulcers: a randomized, double-blind, clinical trial.Lasers in medical science · 2025Trial
- A randomized controlled trial comparing helium-neon laser therapy and infrared laser therapy in patients with diabetic foot ulcer.Lasers in medical science · 2018Trial
- The effect of LED on blood microcirculation during chronic wound healing in diabetic and non-diabetic patients-a prospective, double-blind randomized study.Lasers in medical science · 2017Trial
- The diabetic foot and leg: combined He-Ne and infrared low-intensity lasers improve skin blood perfusion and prevent potential complications. A prospective study on 30 Egyptian patients.Lasers in medical science · 2011Trial
- Diabetes in spotlight: current knowledge and perspectives of photobiomodulation utilization.Frontiers in endocrinology · 2024Review
- Optimal Fluence and Duration of Low-Level Laser Therapy for Efficient Wound Healing in Mice.Annals of dermatology · 2021Article
- The effect of low-level laser therapy (660 nm) on the gene expression involved in tissue repair.Lasers in medical science · 2018Article
- The Effect of Low Level Laser Therapy on Pemphigus Vulgaris Lesions: A Pilot Study.Journal of lasers in medical sciences · 2017Article
- Effect of low-level laser therapy on angiogenesis and matrix metalloproteinase-2 immunoexpression in wound repair.Lasers in medical science · 2017Article
- Effects of a low level laser on the acceleration of wound healing in rabbits.North American journal of medical sciences · 2011Article
- Laser therapy in wound healing associated with diabetes mellitus - Review.Anais brasileiros de dermatologiaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGenerally, the significances of laser photo stimulation are now accepted, but the laser light facilitates wound healing and tissue repair remains poorly understood.
aimsWe have examined the hypothesis that the laser photo stimulation can enhance the collagen production in diabetic wounds using the excision wound model in the Wistar rat model.
methodsThe circular wounds were created on the dorsum of the back of the animals. The animals were divided into two groups. The study group (N = 24) wound was treated with 632.8 nm He-Ne laser at a dose of 3-9 J/cm(2) for 5 days a week until the wounds healed completely. The control group was sham irradiated.
resultA significant increase in the hydroxyproline content and reduction in the wound size were observed in the study group. The pro-healing actions seem to be due to increased collagen deposition as well as better alignment and maturation.
conclusionThe biochemical analysis and clinical observation suggested that 3-6 J/cm(2) laser photo stimulation facilitates the tissue repair process by accelerating collagen production in diabetic wound healing.
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Registered trials
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