Evidence map›Paper›PMID 20101015›Full record

ArticleArchives of internal medicine2010

Physical activity at midlife in relation to successful survival in women at age 70 years or older.

Qi Sun, Mary K Townsend, Olivia I Okereke, Oscar H Franco, Frank B Hu, Francine Grodstein

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of internal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Factors Influencing Physical Activity Participation among Midlife Immigrant Women: A Systematic Review.International journal of environmental research and public health · 2021
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Qi SunDepartment of Nutrition, Harvard School of Public Health, 655 Huntington Ave, Boston, MA 02115, USA. qisun@hsph.harvard.edu
Mary K Townsend
Olivia I Okereke
Oscar H Franco
Frank B Hu
Francine Grodstein

Funding

Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI CORKEY, BARBARA E. · 1992 to 2021
$25.0M
PREVENTING COGNITIVE DECLINE--A PROSPECTIVE STUDYR01AG015424 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI GRODSTEIN, FRANCINE · 1999 to 2003
$2.8M
PROSPECTIVE STUDY OF DIET AND CANCER IN WOMENR01CA040356 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI SPEIZER, FRANK E · 1985 to 2000
$824k
PROSPECTIVE STUDY OF COGNITIVE FUNCTION IN WOMENR29AG013482 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI GRODSTEIN, FRANCINE · 1996 to 2000
$128k
PROSPECTIVE STUDY OF DIET AND CANCER IN WOMENR37CA040356 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI SPEIZER, FRANK E · 1987 to 1994
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NCI NIH HHS CA40356NCI NIH HHS R01 CA040356NIA NIH HHS AG15424NIA NIH HHS R01 AG015424NIA NIH HHS R29 AG013482NIDDK NIH HHS DK46200NIDDK NIH HHS P30 DK046200
6 · The paper itself

Abstract

backgroundPhysical activity is associated with reduced risks of chronic diseases and premature death. Whether physical activity is also associated with improved overall health among those who survive to older ages is unclear.

methodsA total of 13,535 Nurses' Health Study participants who were free of major chronic diseases at baseline in 1986 and had survived to age 70 years or older as of the 1995-2001 period made up the study population. We defined successful survival as no history of 10 major chronic diseases or coronary artery bypass graft surgery and no cognitive impairment, physical impairment, or mental health limitations.

resultsAfter multivariate adjustment for covariates, higher physical activity levels at midlife, as measured by metabolic-equivalent tasks, were significantly associated with better odds of successful survival. Significant increases in successful survival were observed beginning at the third quintile of activity: odds ratios (ORs) (95% confidence intervals [CIs]) in the lowest to highest quintiles were 1 [Reference], 0.98 (0.80-1.20), 1.37 (1.13-1.65), 1.34 (1.11-1.61), and 1.99 (1.66-2.38) (P < .001 for trend). Increasing energy expenditure from walking was associated with a similar elevation in odds of successful survival: the ORs (95% CIs) of successful survival across quintiles of walking were 1 [Reference], 0.99 (0.80-1.21), 1.19 (0.97-1.45), 1.50 (1.24-1.82), and 1.47 (1.22-1.79) (P < .001 for trend).

conclusionThese data provide evidence that higher levels of midlife physical activity are associated with exceptional health status among women who survive to older ages and corroborate the potential role of physical activity in improving overall health.

Indexed as

ExerciseHealth StatusLongevityAdultAgedAgingCognitionEnergy MetabolismFemaleHumansLongitudinal StudiesMental HealthMiddle Aged

Identifiers

PMID20101015
PMCPMC3024209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.