ArticlePharmacology, biochemistry, and behavior2010
Venous plasma nicotine correlates of hormonal effects of tobacco smoking.
Article in Pharmacology, biochemistry, and behavior, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 40 citations in OpenAlex.
- Article
- Observational
- Mediation by elevated prolactin in the relationship between childhood trauma and first-episode drug-naïve schizophrenia.BMC psychiatry · 2025Article
- Article
- Potential Disruption of Systemic Hormone Transport by Tobacco Alkaloids Using Computational Approaches.Toxics · 2022Article
- The mutagenic effect of tobacco smoke on male fertility.Environmental science and pollution research international · 2022Review
- Genome-wide Interaction Study ImplicatesFrontiers in cell and developmental biology · 2022Article
- Stimulus functions of nicotine.Advances in pharmacology (San Diego, Calif.) · 2022Article
- Marijuana Is Associated With a Hormonal Imbalance Among Several Habits Related to Male Infertility: A Retrospective Study.Frontiers in reproductive health · 2022Article
- Prolactin and susceptibility to COVID-19 infection.Medical hypotheses · 2021Article
- Nicotine alters progesterone and estradiol levels during the first trimester of pregnancy in Wistar rats.JBRA assisted reproduction · 2018Article
- Denicotinized versus average nicotine tobacco cigarette smoking differentially releases striatal dopamine.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013Article
- Secondhand tobacco smoke exposure is associated with prolactin but not thyroid stimulating hormone among nonsmoking women seeking in vitro fertilization.Environmental toxicology and pharmacology · 2012Article
- The endocrine effects of nicotine and cigarette smoke.Trends in endocrinology and metabolism: TEM · 2012Review
- Effect of smoking on reproductive hormones and semen parameters of infertile Saudi Arabians.Urology annalsArticle
- Post-Traumatic Stress Disorder Is a Significant Risk Factor for Central Serous Chorioretinopathy in Male Veterans.American journal of men's healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The present study resolves some of the discrepancies in the literature by correlating the effects of tobacco smoking on hormone release with venous plasma nicotine levels. Cortisol, prolactin, and beta-endorphin concentrations were measured. Habitual male tobacco users smoked denicotinized (very low nicotine) and average nicotine cigarettes in the morning after overnight tobacco abstinence. Several venous blood samples were withdrawn before and during the smoking sessions for subsequent analyses. The increases in plasma nicotine correlated well with plasma cortisol and prolactin levels (correlation coefficients r=0.66 and 0.53, respectively, p<0.05). This study quantifies the well known increase in plasma cortisol and prolactin after nicotine postsmoking for about 1h with peak plasma levels up to 35 ng/ml. Contrary to most abused drugs which release dopamine and decrease prolactin, nicotine concentration correlated with increased prolactin release. Increases in maximal plasma beta-endorphin levels following tobacco smoking were barely statistically significant with insufficient data to obtain a correlation coefficient.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.