ReviewFEBS letters2010
Cooperative elastic stresses, the hydrophobic effect, and lipid tilt in membrane remodeling.
Review in FEBS letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Article
- Continuum Models of Membrane Fusion: Evolution of the Theory.International journal of molecular sciences · 2020Review
- GTP hydrolysis promotes disassembly of the atlastin crossover dimer during ER fusion.The Journal of cell biology · 2018Article
- Lateral Membrane Heterogeneity Regulates Viral-Induced Membrane Fusion during HIV Entry.International journal of molecular sciences · 2018Article
- Switching between Successful and Dead-End Intermediates in Membrane Fusion.International journal of molecular sciences · 2017Article
- The crossover conformational shift of the GTPase atlastin provides the energy driving ER fusion.The Journal of cell biology · 2017Article
- The advantage of channeling nucleotides for very processive functions.F1000Research · 2017Review
- cBid, Bax and Bcl-xL exhibit opposite membrane remodeling activities.Cell death & disease · 2016Article
- A hemi-fission intermediate links two mechanistically distinct stages of membrane fission.Nature · 2015Article
- A membrane proximal helix in the cytosolic domain of the human APP interacting protein LR11/SorLA deforms liposomes.Biochimica et biophysica acta · 2015Article
- Cholesterol-dependent membrane fusion induced by the gp41 membrane-proximal external region-transmembrane domain connection suggests a mechanism for broad HIV-1 neutralization.Journal of virology · 2014Article
- The three lives of viral fusion peptides.Chemistry and physics of lipids · 2014Review
- Geometric catalysis of membrane fission driven by flexible dynamin rings.Science (New York, N.Y.) · 2013Article
- The role of lateral tension in calcium-induced DPPS vesicle rupture.Langmuir : the ACS journal of surfaces and colloids · 2012Article
- A new view of the lethal apoptotic pore.PLoS biology · 2012Review
- Lipid-mediated endocytosis.Cold Spring Harbor perspectives in biology · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
One of the fundamental properties of biological membranes is the high lateral integrity provided by the lipid bilayer, the structural core and the foundation of their barrier function. This tensile strength is due to the intrinsic properties of amphiphilic lipid molecules, which spontaneously self-assemble into a stable bilayer structure due to the hydrophobic effect. In the highly dynamic life of cellular membranes systems, however, this integrity has to be regularly compromised. One of the emerging puzzles is the mechanism of localized rupture of lipid monolayer, the formation of tiny hydrophobic patches and flipping of lipid tails between closely apposed monolayers. The energy cost of such processes is prohibitively high, unless cooperative deformations in a small membrane patch are carefully organized. Here we review the latest experimental and theoretical data on how such deformations can be conducted, specifically describing how elastic stresses yield tilting of lipids leading to cooperative restructuring of lipid monolayers. Proteins specializing in membrane remodeling assemble into closely packed circular complexes to arrange these deformations in time and space.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.