ArticleScandinavian journal of infectious diseases2010
Burden of respiratory syncytial virus in hospitalized infants and young children in Amman, Jordan.
Article in Scandinavian journal of infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Respiratory syncytial virus hospitalization and mortality: Systematic review and meta-analysis.Pediatric pulmonology · 2017Pooled it
- Cost of management of severe pneumonia in young children: systematic analysis.Journal of global health · 2016Pooled it
- Epidemiology of respiratory syncytial virus in young, hospitalized children in Jordan: a prospective viral surveillance study.Microbiology spectrum · 2025Article
- Respiratory syncytial virus hospitalization costs, rates, and seasonality in Asia: a systematic review and meta-analysis.EClinicalMedicine · 2025Review
- Infectious disease burden and surveillance challenges in Jordan and Palestine: a systematic review and meta-analysis.Frontiers in digital health · 2025Review
- Article
- Respiratory Disease Surveillance in the Middle East and Latin America during the COVID-19 Pandemic, 2020-2022.Emerging infectious diseases · 2024Article
- Respiratory syncytial virus in pediatric patients admitted to a tertiary center in Amman: clinical characteristics, and age-related patterns.BMC pediatrics · 2024Article
- Article
- Article
- Household economic burden of childhood severe pneumonia in Bangladesh: a cost-of-illness study.Archives of disease in childhood · 2021Article
- Article
- Systematic Review of the Respiratory Syncytial Virus (RSV) Prevalence, Genotype Distribution, and Seasonality in Children from the Middle East and North Africa (MENA) Region.Microorganisms · 2020Article
- Viral Surveillance of Children with Acute Respiratory Infection in Two Main Hospitals in Northern Jordan, Irbid, during Winter of 2016.Journal of pediatric infectious diseases · 2020Article
- Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan.BMJ open · 2018Article
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- High burden of RSV hospitalization in very young children: a data linkage study.Epidemiology and infection · 2016Article
- Article
- Human rhinovirus C infections in pediatric hematology and oncology patients.Pediatric transplantation · 2015Article
- Vitamin D deficiency among newborns in Amman, Jordan.Global journal of health science · 2013Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
Abstract
Acute respiratory infections (ARI) play a major role in hospitalizations in the Middle East, but the specific viral causes are unknown. We conducted prospective viral surveillance in children <5 y of age admitted with ARI and/or fever at 2 dissimilar hospitals in Amman, Jordan during peak respiratory syncytial virus (RSV) season. We collected prospective clinical and demographic data and obtained nose/throat swabs for testing for RSV by real-time polymerase chain reaction (RT-PCR). We obtained clinical and laboratory data for 728/743 (98%) subjects enrolled. The children's median age was 4.3 months, 58.4% were males, 87% were breastfed, 4% attended day care, 67% were exposed to smokers, 7% were admitted to the intensive care unit, and 0.7% died (n = 5). Out of 728 subjects, 467 (64%) tested positive by RT-PCR for RSV. Comparing RSV-positive with RSV-negative subjects, the RSV-positive subjects had lower median age (3.6 vs 6.4 months, p < 0.001) and fewer males (55% vs 64%, p = 0.02). RSV-positive children had higher rates of oxygen use (72% vs 42%, p < 0.001), a longer hospital stay (5 vs 4 days, p = 0.001), and higher hospital charges (US$538 vs US$431, p < 0.001) than RSV-negative children. In young hospitalized Jordanian infants, the medical and financial burden of RSV was found to be high. Effective preventive measures, such as an RSV vaccine, would have a significant beneficial impact.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.