SynthesisPLoS neglected tropical diseases2010
Control of visceral leishmaniasis in latin america-a systematic review.
Synthesis in PLoS neglected tropical diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
141 citing papers in PubMed, 13 syntheses or guidelines pooled it, 371 citations in OpenAlex.
- World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence-Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis.Veterinary dermatology · 2025Guideline
- Leishmaniasis in deployed military populations: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2025Pooled it
- Efficacy and community-effectiveness of insecticide treated nets for the control of visceral leishmaniasis: A systematic review.PLoS neglected tropical diseases · 2022Pooled it
- Factors associated with human visceral leishmaniasis cases during urban epidemics in Brazil: a systematic review.Parasitology · 2021Pooled it
- Effectiveness of vector control methods for the control of cutaneous and visceral leishmaniasis: A meta-review.PLoS neglected tropical diseases · 2021Pooled it
- Pooled it
- Vector and reservoir control for preventing leishmaniasis.The Cochrane database of systematic reviews · 2015Pooled it
- Risk factors for adverse prognosis and death in American visceral leishmaniasis: a meta-analysis.PLoS neglected tropical diseases · 2014Pooled it
- Low quality evidence of epidemiological observational studies on leishmaniasis in Brazil.PloS one · 2014Pooled it
- Control of visceral leishmaniasis in Brazil: recommendations from Brasileish.Parasites & vectors · 2013Guideline
- Factors associated with visceral leishmaniasis in the americas: a systematic review and meta-analysis.PLoS neglected tropical diseases · 2013Pooled it
- Pooled it
- Evaluation of rK39 rapid diagnostic tests for canine visceral leishmaniasis: longitudinal study and meta-analysis.PLoS neglected tropical diseases · 2013Pooled it
- Efficacy and safety of available treatments for visceral leishmaniasis in Brazil: A multicenter, randomized, open label trial.PLoS neglected tropical diseases · 2017Trial
- Effectiveness of insecticide spraying and culling of dogs on the incidence of Leishmania infantum infection in humans: a cluster randomized trial in Teresina, Brazil.PLoS neglected tropical diseases · 2014Trial
- Controlling mountain-type zoonotic visceral leishmaniasis in China: Current progress and challenges through a One Health lens.One health (Amsterdam, Netherlands) · 2026Article
- Strengthening health management information systems for Chagas disease: a multi-level qualitative study in Bolivia and Paraguay.Lancet regional health. Americas · 2026Article
- Advances and Challenges in the Diagnosis of Vector-Borne Protozoal Infections in Veterinary Medicine.Pathogens (Basel, Switzerland) · 2026Review
- Epidemiological Shifts in Visceral Leishmaniasis Incidence, Relapse, and Mortality in Brazil, 2007-2023: Analysis Using the National Notifiable Diseases Information System.Open forum infectious diseases · 2026Article
- Neglected parasitic diseases from a one-health perspective: American trypanosomiasis and leishmaniasis in dogs and humans in the Bolivian Chaco.Parasites & vectors · 2025Article
81 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile three countries in South Asia decided to eliminate anthroponotic visceral leishmaniasis (VL) by 2015, its control in other regions seems fraught with difficulties. Is there a scope for more effective VL control in the Americas where transmission is zoonotic? We reviewed the evidence on VL control strategies in Latin America-diagnosis, treatment, veterinary interventions, vector control-with respect to entomological and clinical outcomes. METHODOLOGY/PRINCIPAL
findingsWe searched the electronic databases of MEDLINE, LILACS, and the Cochrane Central Register of Controlled Trials, from 1960 to November 2008 and references of selected articles. Intervention trials as well as observational studies that evaluated control strategies of VL in the Americas were included. While the use of rapid diagnostic tests for VL diagnosis seems well established, there is a striking lack of evidence from clinical trials for drug therapy and few well designed intervention studies for control of vectors or canine reservoirs.
conclusionElimination of zoonotic VL in the Americas does not seem a realistic goal at this point given the lack of political commitment, gaps in scientific knowledge, and the weakness of case management and surveillance systems. Research priorities and current strategies should be reviewed with the aim of achieving better VL control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.