Evidence map›Paper›PMID 20098606›Full record

ArticleMarine drugs2009

Effects and interactions of medium components on laccase from a marine-derived fungus using response surface methodology.

Donna D'Souza-Ticlo, Sandeep Garg, Chandralata Raghukumar

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Donna D'Souza-TicloMarine Biotechnology Laboratory, National Institute of Oceanography, Council of Scientific & Industrial Research, Dona Paula, Goa, India.
Sandeep Garg
Chandralata Raghukumar
Council of Scientific and Industrial Research · INGoa University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of various synthetic medium components and their interactions with each other ultimately impact laccase production in fungi. This was studied using a laccase-hyper-producing marine-derived basidiomycete, Cerrena unicolor MTCC 5159. Inducible laccases were produced in the idiophase only after addition of an inducer such as CuSO(4). Concentration of carbon and nitrogen acted antagonistically with respect to laccase production. A combination of low nitrogen and high carbon concentration favored both biomass and laccase production. The most favorable combination resulted in 917 U L(-1) of laccase. After sufficient growth had occurred, addition of a surfactant such as Tween 80 positively impacted biomass and increased the laccase activity to around 1,300 U L(-1). Increasing the surface to volume ratio of the culture vessel further increased its activity to almost 2,000 U L(-1).

Indexed as

BiomassBiostatisticsCulture MediaFungiHydrogen-Ion ConcentrationLaccaseSubstrate SpecificityCulture MediaLaccaseCentral Composite Design and Plackett Burman Designlaccasemarine-derived basidiomyceteresponse surface methodology

Identifiers

PMID20098606
PMCPMC2810131
OpenAlexW2122827740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.