ArticleExperimental and clinical cardiology2009
The relationship between serum ferritin levels and electrocardiogram characteristics in acutely ill patients.
Article in Experimental and clinical cardiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Abnormality prediction and forecasting of laboratory values from electrocardiogram signals using multimodal deep learning.Scientific reports · 2025Article
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac arrhythmias are common comorbidities among acutely ill patients admitted to hospitals. An abnormal iron metabolism may contribute to the abnormalities in the conduction and propagation of action potentials through myocardium.
objectiveTo determine whether serum indexes of iron metabolism correlate with electrocardiogram (ECG) changes.
methodsIn the present retrospective, pilot chart review, serum levels of iron, ferritin, Na(+), K(+), Mg(2+), Ca(2+) and total iron-binding capacity in 77 hospitalized patients with acute illness were correlated with ECG variables.
resultsThe serum ferritin level correlated strongly (r=0.49) with QT/QTs interval. There were three subjects with QT prolongation (longer than 450 ms) within the high serum ferritin (576 ng/mL or greater) group versus subjects with low ferritin. Multiple regression analysis showed that serum ferritin level and serum iron level contributed to the variance in the QT/QTs prolongation. No other correlation between the studied serum markers and ECG characteristics were found.
conclusionThe present study suggests that serum ferritin and iron levels affect the QT interval in a variety of medical conditions, possibly contributing to the emergence of fatal cardiac arrhythmias.
Indexed as
Identifiers
20098576PMC2807778W227877947What OpenQuestion holds
Registered trials
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