ReviewVirus research2010
A systematic approach to virus-virus interactions.
Review in Virus research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
122 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Viral Co-Infection in Bats: A Systematic Review.Viruses · 2023Pooled it
- Respiratory viral co-infections in patients with COVID-19 and associated outcomes: A systematic review and meta-analysis.Reviews in medical virology · 2023Pooled it
- The role of viral co-infections in the severity of acute respiratory infections among children infected with respiratory syncytial virus (RSV): A systematic review and meta-analysis.Journal of global health · 2020Pooled it
- Clinical disease severity of respiratory viral co-infection versus single viral infection: a systematic review and meta-analysis.PloS one · 2014Pooled it
- Interference Between Respiratory Syncytial Virus and Human Rhinovirus Infection in Infancy.The Journal of infectious diseases · 2017Trial
- Article
- High-throughput sequencing-based virome analysis reveals genomic diversity and recombination of tomato-infecting viruses in Korea.Scientific reports · 2026Article
- Interaction analysis of non-bacterial respiratory pathogens during and after the coronavirus disease 2019 pandemic in two cities along the eastern coast of China.Pediatric investigation · 2026Article
- Shifts in epidemic patterns and age dynamics of RSV, IFV, and SARS-CoV-2 in Chinese children following COVID-19 non-pharmaceutical intervention relaxation, 2017 - 2024.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Observational
- Usurpativirus massiliensis, a new giant virus related to clandestinovirus.Virology journal · 2025Article
- The Biology of Nucleus-Forming Jumbo Phages.Annual review of genetics · 2025Review
- Coinfection with Respiratory Pathogens and Dengue Disease Severity in Puerto Rico, 2012-2024.The American journal of tropical medicine and hygiene · 2025Article
- Influenza A virus interferes with respiratory syncytial virus in mice and reconstituted human airway epithelium.Microbiology spectrum · 2025Article
- Population-level respiratory virus-virus interactions, Puerto Rico, 2013-2023.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2025Article
- Making sense of the virome in light of evolution and ecology.Proceedings. Biological sciences · 2025Review
- Multiple Respiratory Virus Detection in Acute Respiratory Infection Patients in Mie Prefecture, Japan, 2021-2023.Viruses · 2025Article
- Navigating a Fine Balance: Point-Mutant Cheater Viruses Disrupt the Viral Replication Cycle.Molecular biology and evolution · 2025Article
- Shattering the Amyloid Illusion: The Microbial Enigma of Alzheimer's Disease Pathogenesis-From Gut Microbiota and Viruses to Brain Biofilms.Microorganisms · 2025Review
- N Protein of Tomato Spotted Wilt Virus Proven to Be Antagonistic Against Tomato Yellow Leaf Curl Virus in Nicotiana benthamiana.Molecular plant pathology · 2025Article
- Characterizing the interactions between influenza and respiratory syncytial viruses and their implications for epidemic control.Nature communications · 2024Article
62 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A virus-virus interaction is a measurable difference in the course of infection of one virus as a result of a concurrent or prior infection by a different species or strain of virus. Many such interactions have been discovered by chance, yet they have rarely been studied systematically. Increasing evidence suggests that virus-virus interactions are common and may be critical to understanding viral pathogenesis in natural hosts. In this review we propose a system for classifying virus-virus interactions by organizing them into three main categories: (1) direct interactions of viral genes or gene products, (2) indirect interactions that result from alterations in the host environment, and (3) immunological interactions. We have so far identified 15 subtypes of interaction and assigned each to one of these categories. It is anticipated that this framework will provide for a more systematic approach to investigating virus-virus interactions, both at the cellular and organismal levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.