Evidence map›Paper›PMID 20091878›Full record

ReviewBiopolymers2010

Protein- and peptide-modified synthetic polymeric biomaterials.

Ohm D Krishna, Kristi L Kiick

Open access · greenAbstract readReview
In one paragraph

Review in Biopolymers, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 196 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Frontiers in bioengineering and biotechnology · 2023
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Investigating Active Learning and Meta-Learning for Iterative Peptide Design.Journal of chemical information and modeling · 2021
    Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Tunable Polymeric Scaffolds for Enzyme Immobilization.Frontiers in bioengineering and biotechnology · 2020
    Review
  19. Article
  20. Production of a Recombinant Non-Hydroxylated Gelatin Mimetic inJournal of functional biomaterials · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ohm D KrishnaDepartment of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA.
Kristi L Kiick
Biotechnology Institute · USUniversity of Delaware · US

Funding

UDE COBRE: STRAINED MOLECULES FOR SYNTHESIS OF UNNATURAL AMINO ACIDSP20RR017716 · NCRR · UNIVERSITY OF DELAWARE · PI SULLIVAN, MILLICENT O · 2002 to 2011
$16.9M
Biotechnology Research Partnerships Renewal: Aggregation of Therapeutic ProteinsR01EB006006 · NIBIB · UNIVERSITY OF COLORADO · PI RANDOLPH, THEODORE W · 2006 to 2017
$7.2M
NCRR NIH HHS 1-P20-RR017716NCRR NIH HHS P20 RR017716NIBIB NIH HHS 1-R01-EB006006-01NIBIB NIH HHS R01 EB006006
6 · The paper itself

Abstract

This review presents an overview on bio-hybrid approaches of integrating the structural and functional features of proteins and peptides with synthetic polymers and the resulting unique properties in such hybrids, with a focus on bioresponsive/bioactive systems with biomaterials applications. The review is divided in two broad sections. First, we describe several examples of bio-hybrids produced by combining versatile synthetic polymers with proteins/enzymes and drugs that have resulted in (1) hybrid materials based on responsive polymers, (2) responsive hydrogels based on enzyme-catalyzed reactions, protein-protein interactions and protein-drug sensing, and (3) dynamic hydrogels based on conformational changes of a protein. Next, we present hybrids produced by combining synthetic polymers with peptides, classified based on the properties of the peptide domain: (1) peptides with different conformations, such as alpha-helical, coiled-coil, and beta-sheet; (2) peptides derived from structural protein domains such as silk, elastin, titin, and collagen; and (3) peptides with other biofunctional properties such as cell-binding domains and enzyme-recognized degradation domains.

Indexed as

Biocompatible MaterialsHumansHydrogelsModels, MolecularPeptidesPolymersProtein ConformationProteinsBiocompatible MaterialsHydrogelsPeptidesPolymersProteins

Identifiers

PMID20091878
PMCPMC4437713
OpenAlexW2112632147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.