ReviewBiopolymers2010
Fibrillar peptide gels in biotechnology and biomedicine.
Review in Biopolymers, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed.
- Structural information in therapeutic peptides: Emerging applications in biomedicine.FEBS open bio · 2025Review
- Efficacy of novel endoscopic hemostatic agent for bleeding control and prevention: Results from a prospective, multicenter national registry.Endoscopy international open · 2024Article
- Injectable nanofibrillar hydrogels based on charge-complementary peptide co-assemblies.Biomaterials science · 2021Article
- Article
- Strategy to Identify Improved N-Terminal Modifications for Supramolecular Phenylalanine-Derived Hydrogelators.Langmuir : the ACS journal of surfaces and colloids · 2019Article
- Hydrogels formed by anammox extracellular polymeric substances: structural and mechanical insights.Scientific reports · 2019Article
- Peptide Tectonics: Encoded Structural Complementarity Dictates Programmable Self-Assembly.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Review
- Peptide Self-Assembly into Hydrogels for Biomedical Applications Related to Hydroxyapatite.Gels (Basel, Switzerland) · 2019Review
- Self-Assembling Peptides as Extracellular Matrix Mimics to Influence Stem Cell's Fate.Frontiers in chemistry · 2019Review
- A light-responsive multienzyme complex combining cascade enzymes within a peptide-based matrix.RSC advances · 2018Article
- Self-assembling soft structures for intracellular NO release and promotion of neurite outgrowth.Chemical science · 2017Article
- Harnessing supramolecular peptide nanotechnology in biomedical applications.International journal of nanomedicine · 2017Review
- Engineering responsive supramolecular biomaterials: Toward smart therapeutics.Bioengineering & translational medicine · 2016Review
- This paper is the winner of an SFB Award in the Hospital Intern, Residency category: Peptide biomaterials raising adaptive immune responses in wound healing contexts.Journal of biomedical materials research. Part A · 2016Article
- Bio-inspired 3D microenvironments: a new dimension in tissue engineering.Biomedical materials (Bristol, England) · 2016Review
- Thermal stability of self-assembled peptide vaccine materials.Acta biomaterialia · 2016Article
- Multicomponent dipeptide hydrogels as extracellular matrix-mimetic scaffolds for cell culture applications.Chemical communications (Cambridge, England) · 2015Article
- Sequence effects of self-assembling multidomain peptide hydrogels on encapsulated SHED cells.Biomacromolecules · 2014Article
- Formation of ordered biomolecular structures by the self-assembly of short peptides.Journal of visualized experiments : JoVE · 2013Article
- Self-assembly and gelation properties of glycine/leucine Fmoc-dipeptides.The European physical journal. E, Soft matter · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Peptides, peptidomimetics, and peptide derivatives that self-assemble into fibrillar gels have received increasing interest as synthetic extracellular matrices for applications in 3D cell culture and regenerative medicine. Recently, several of these fibrillizing molecules have been functionalized with bioactive components and chemical features such as cell-binding ligands, degradable sequences, drug eluting compounds, and cross-linkable groups, thereby producing gels that can reliably display multiple factors simultaneously. This capacity for incorporating precise levels of many different biological and chemical factors is advantageous given the natural complexity of cell-matrix interactions that many current biomaterial strategies seek to mimic. In this review, recent efforts in the area of fibril-forming peptide materials are described, and advantages of biomaterials containing multiple modular elements are outlined. In addition, a few hurdles and open questions surrounding fibrillar peptide gels are discussed, including issues of the materials' structural heterogeneity, challenges in fully characterizing the diversity of their self-assembled structures, and incomplete knowledge of how the materials are processed in vivo.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.