Evidence map›Paper›PMID 20091609›Full record

SynthesisThe Cochrane database of systematic reviews2010

Braces for idiopathic scoliosis in adolescents.

Stefano Negrini, Silvia Minozzi, Josette Bettany-Saltikov, Fabio Zaina, Nachiappan Chockalingam, Theodoros B Grivas, Tomasz Kotwicki, Toru Maruyama, Michele Romano, Elias S Vasiliadis

Open access · bronzeAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Predictive factors for brace treatment outcome in adolescent idiopathic scoliosis: a best-evidence synthesis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2019
    Pooled it
  2. Braces for idiopathic scoliosis in adolescents.The Cochrane database of systematic reviews · 2015
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Exercises for adolescent idiopathic scoliosis.The Cochrane database of systematic reviews · 2012
    Pooled it
  6. Trial
  7. Trial
  8. Effects of bracing in adolescents with idiopathic scoliosis.The New England journal of medicine · 2013
    Trial
  9. Trial
  10. Prospective evaluation of physical activity in patients with idiopathic scoliosis or kyphosis receiving brace treatment.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2011
    Trial
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Bracing In The Treatment Of Adolescent Idiopathic Scoliosis: Evidence To Date.Adolescent health, medicine and therapeutics · 2019
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 5 countries.

Stefano NegriniISICO (Italian Scientific Spine Institute), Via Roberto Bellarmino 13/1, Milan, Italy, 20141.
Silvia Minozzi
Josette Bettany-Saltikov
Fabio Zaina
Nachiappan Chockalingam
Theodoros B Grivas
Tomasz Kotwicki
Toru Maruyama
Michele Romano
Elias S Vasiliadis
Istituto Scientifico Italiano Colonna Vertebrale · ITAssociation for Symbolic Logic · USSaitama Medical University · JPTeesside University · GBThriasio General Hospital of Elefsina · GRTzaneion General Hospital · GRUniversity of Staffordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescent Idiopathic Scoliosis (AIS) is a three-dimensional deformity of the spine. While AIS can progress during growth and cause a surface deformity, it is usually not symptomatic. However, in adulthood, if the final spinal curvature surpasses a certain critical threshold, the risk of health problems and curve progression is increased. Braces are traditionally recommended to stop curvature progression in some countries and criticized in others. They generally need to be worn full time, with treatment extending over years.

objectivesTo evaluate the efficacy of bracing in adolescent patients with AIS. SEARCH STRATEGY: The following databases (up to July 2008) were searched with no language limitations: the Cochrane Central Register of Controlled Trials, MEDLINE (from January 1966), EMBASE (from January 1980), CINHAL (from January 1982) and reference lists of articles. An extensive handsearch of the grey literature was also conducted. SELECTION CRITERIA: Randomised controlled trials and prospective cohort studies comparing braces with no treatment, other treatment, surgery, and different types of braces. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed trial quality and extracted data. MAIN

resultsWe included two studies. There was very low quality evidence from one prospective cohort study with 286 girls that a brace curbed curve progression at the end of growth (success rate 74% (95% CI: 52% to 84%)), better than observation (success rate 34% (95% CI:16% to 49%)) and electrical stimulation (success rate 33% (95% CI:12% to 60%)). There is low quality evidence from one RCT with 43 girls that a rigid brace is more successful than an elastic one (SpineCor) at curbing curve progression when measured in Cobb degrees, but there were no significant differences between the two groups in the subjective perception of daily difficulties associated with wearing the brace. AUTHORS'

conclusionsThere is very low quality evidence in favour of using braces, making generalization very difficult. Further research could change the actual results and our confidence in them; in the meantime, patients' choices should be informed by multidisciplinary discussion. Future research should focus on short and long-term patient-centred outcomes, in addition to measures such as Cobb angles. RCTs and prospective cohort studies should follow both the Scoliosis Resarch Society (SRS) and Society on Scoliosis Orthopaedic and Rehabilitation Treatment (SOSORT) criteria for bracing studies.

Indexed as

BracesAdolescentChildCohort StudiesFemaleHumansRandomized Controlled Trials as TopicScoliosis

Identifiers

PMID20091609
OpenAlexW4211241334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.