ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2010
Central nervous system congenital malformations in a developing country: issues and challenges against their prevention.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Investigating the use of ultrasonography for the antenatal diagnosis of structural congenital anomalies in low-income and middle-income countries: a systematic review.BMJ paediatrics open · 2020Pooled it
- Surgical treatment and outcomes of neural tube defects at the university of Gondar Comprehensive Specialized Hospital, Ethiopia: a two-year retrospective review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- The Importance of Neurosurgical Intervention and Surgical Timing for Management of Pediatric Patients with Myelomeningoceles in Bangladesh.World neurosurgery · 2024Article
- Knowledge of Neural Tube Defects and Prevention Through Folic Acid Use Among Women in Faisalabad, Punjab, Pakistan: A Cross-Sectional Survey.International journal of women's health · 2022Article
- Prevalence of Pediatric Surgical Conditions Across Somaliland.JAMA network open · 2019Observational
- Spina bifida: a prospective study from a single neurosurgical center based on the National Hospital in Niamey (Niger).Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- The development and evaluation of content validity of the Zambia Spina Bifida Functional Measure: Preliminary studies.African journal of disability · 2017Article
- Access to health care for children with neural tube defects: Experiences of mothers in Zambia.African journal of disability · 2016Article
- Awareness and uptake of measures for preventing CNS birth defects among mothers of affected children in a sub-Saharan African neurosurgeon's practice.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
- Epidemiology, prenatal management, and prevention of neural tube defects.Saudi medical journal · 2014Review
- Determinants of folic acid intake during preconception and in early pregnancy by mothers in Ibadan, Nigeria.The Pan African medical journal · 2014Article
- Influence of congenital central nervous system malformations on postoperative complications following placement of cerebrospinal fluid shunts in pediatric and adolescent patients.Wiener klinische Wochenschrift · 2014Article
- Prevention of myelomeningocele: African perspectives.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013Review
- Awareness of spina bifida and periconceptional use of folic acid among pregnant women in a developing economy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLittle efforts are geared towards prevention of CNS anomalies in the developing countries.
methodsA 1-year prospective cross-sectional analysis of the cases of CNS congenital anomalies seen in a Nigerian neurosurgical unit. This included both the children's and parents' sociodemographics, the profiles of the CNS anomalies, and the maternal obstetric health behaviors toward primary and/or secondary prevention of the anomalies. Statistical analysis was done with the Pearson's chi-square (or Fishers' exact) test. Level of significance set at P < 0.05.
resultsThere were 54 cases of cranial and spinal gross CNS anomalies, including 32 neural tube defects; two thirds of the parents were low-income earners, and half had only basic education. Thirty percent of the pregnancies were unbooked; the mean gestational age (GA) at booking and commencement of obstetric micronutrient supplementation was 4.6 months. No case had periconceptional folic acid supplementation. Obstetric ultrasonography was performed late in pregnancy (mean GA 6 months), made positive diagnosis of CNS anomaly in only 14%, and was performed mainly in unsupervised private clinic settings in 98%.
conclusionsLittle or no attention is currently paid to the prevention of CNS congenital anomalies in much of the low- and middle-income countries of the world. There is a great need to regulate the practice of obstetric ultrasonography in Nigeria. There is even a much greater, more fiercely urgent need to ensure periconceptional folic acid supplementation for all women of childbearing age through appropriate food fortification in these societies.
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