ArticleMolecular vision2010
Expression profiles during dedifferentiation in newt lens regeneration revealed by expressed sequence tags.
Article in Molecular vision, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Multi-omics analysis reveals the evolution, function, and regulatory mechanisms of SPF pheromones in Anurans.Communications biology · 2024Article
- Expression profiling of stemness markers in testicular germline stem cells from neonatal and adult Swiss albino mice during their transdifferentiation in vitro.Stem cell research & therapy · 2024Article
- The miRNA-34a/Sirt1/p53 pathway in a rat model of lens regeneration.Annals of translational medicine · 2022Article
- Lens regeneration in humans: using regenerative potential for tissue repairing.Annals of translational medicine · 2020Review
- Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte.Stem cells (Dayton, Ohio) · 2019Article
- Using transcriptomics to enable a plethodontid salamander (Bolitoglossa ramosi) for limb regeneration research.BMC genomics · 2018Article
- Diverse Evolutionary Origins and Mechanisms of Lens Regeneration.Molecular biology and evolution · 2018Review
- TISSUE REPAIR AND EPIMORPHIC REGENERATION: AN OVERVIEW.Current pathobiology reports · 2018Article
- Epigenetic Control of Reprogramming and Transdifferentiation by Histone Modifications.Stem cell reviews and reports · 2016Review
- Chemical transdifferentiation: closer to regenerative medicine.Frontiers of medicine · 2016Review
- Beyond sodefrin: evidence for a multi-component pheromone system in the model newt Cynops pyrrhogaster (Salamandridae).Scientific reports · 2016Article
- Muse Cells: Nontumorigenic Pluripotent Stem Cells Present in Adult Tissues-A Paradigm Shift in Tissue Regeneration and Evolution.Stem cells international · 2016Review
- Review
- High pheromone diversity in the male cheek gland of the red-spotted newt Notophthalmus viridescens (Salamandridae).BMC evolutionary biology · 2015Article
- Cell signaling pathways in vertebrate lens regeneration.Current topics in microbiology and immunology · 2013Review
- Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema.PLoS computational biology · 2013Article
- Transdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signalling.BMC developmental biology · 2011Article
- Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration.Nature reviews. Molecular cell biology · 2011Review
- Generation of Induced Pluripotent Stem (iPS) Cells by Nuclear Reprogramming.Stem cells international · 2011Article
- Molecular and cellular aspects of amphibian lens regeneration.Progress in retinal and eye research · 2010Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
purposeThe adult newt can regenerate lens from pigmented epithelial cells (PECs) of the dorsal iris via dedifferentiation. The purpose of this research is to obtain sequence resources for a newt lens regeneration study and to obtain insights of dedifferentiation at the molecular level.
methodsmRNA was purified from iris during dedifferentiation and its cDNA library was constructed. From the cDNA library 10,449 clones were sequenced and analyzed.
resultsFrom 10,449 reads, 780 contigs and 1,666 singlets were annotated. The presence of several cancer- and apoptosis-related genes during newt dedifferentiation was revealed. Moreover, several candidate genes, which might participate in reprogramming during dedifferentiation, were also found.
conclusionsThe expression of cancer- and apoptosis-related genes could be hallmarks during dedifferentiation. The expression sequence tag (EST) resource is useful for the future study of newt dedifferentiation, and the sequence information is available in GenBank (accession numbers; FS290155-FS300559).
Indexed as
Identifiers
20090923PMC2807617W2127626473What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.