ArticleAnti-inflammatory & anti-allergy agents in medicinal chemistry2009
Pathogenic Bacterial Proteins and their Anti-Inflammatory Effects in the Eukaryotic Host.
Article in Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Statewide Linkage Study ofJournal of registry management · 2024Article
- Protective Effects of High-Fat Diet against Murine Colitis in Association with Leptin Signaling and Gut Microbiome.Life (Basel, Switzerland) · 2022Article
- Heightened Virulence ofInfection and immunity · 2021Article
- AvrA Exerts Inhibition of NF-κB Pathway in Its NaïveInternational journal of molecular sciences · 2020Article
- Oral and intestinal bacterial exotoxins: Potential linked to carcinogenesis.Progress in molecular biology and translational science · 2020Review
- Review
- Non-specific Effects of Live Attenuated Pertussis Vaccine Against Heterologous Infectious and Inflammatory Diseases.Frontiers in immunology · 2018Review
- Article
- Presence ofOncotarget · 2017Article
- Bacterial protein AvrA stabilizes intestinal epithelial tight junctions via blockage of the C-Jun N-terminal kinase pathway.Tissue barriers · 2015Article
- AvrA effector protein of Salmonella enterica serovar Enteritidis is expressed and translocated in mesenteric lymph nodes at late stages of infection in mice.Microbiology (Reading, England) · 2014Article
- Consistent activation of the β-catenin pathway by Salmonella type-three secretion effector protein AvrA in chronically infected intestine.American journal of physiology. Gastrointestinal and liver physiology · 2012Article
- Wingless homolog Wnt11 suppresses bacterial invasion and inflammation in intestinal epithelial cells.American journal of physiology. Gastrointestinal and liver physiology · 2011Article
- IQGAP1 in microbial pathogenesis: Targeting the actin cytoskeleton.FEBS letters · 2011Review
- The inflammatory cytokine tumor necrosis factor modulates the expression of Salmonella typhimurium effector proteins.Journal of inflammation (London, England) · 2010Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Bacteria use multiple strategies to bypass the inflammatory responses in order to survive in the host cells. In this review, we discuss the mechanism of the bacerial proteins in inhibiting inflammation. We highlight the anti-inflammatory roles of the type three secretion proteins including Salmonella AvrA, Enteropathogenic Escherichia coli Cif, and Yersinia YopJ, Staphylococcus aureus extracellular adherence protein, and Chlamydia proteins. We also discuss the research progress on the structures of these anti-inflammatory bacterial proteins. The current therapeutic methods for diseases, such as inflammatory bowel diseases, sclerosis, lack influence on the course of chronic inflammation and infection. Therefore, based on the molecular mechanism of the anti-inflammatory bacterial proteins and their 3-Dimension structure, we can design new peptides or non-peptidic molecules that serve as anti-inflammatory drugs without the possible side effect of promoting bacterial infection.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.