Evidence map›Paper›PMID 20089425›Full record

ArticleVeterinary journal (London, England : 1997)2011

Respiratory function and pulmonary lesions in pigs infected with porcine reproductive and respiratory syndrome virus.

Judith Wagner, Annette Kneucker, Elisabeth Liebler-Tenorio, Vicky Fachinger, Melanie Glaser, Stefan Pesch, Michael P Murtaugh, Petra Reinhold

Open access · greenAbstract read
In one paragraph

Article in Veterinary journal (London, England : 1997), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Lung function monitoring in the era of respiratory pandemics.Clinical physiology and functional imaging · 2020
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Judith WagnerInstitute of Molecular Pathogenesis in the Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Naumburger Str 96a, 07743 Jena, Germany.
Annette Kneucker
Elisabeth Liebler-Tenorio
Vicky Fachinger
Melanie Glaser
Stefan Pesch
Michael P Murtaugh
Petra Reinhold
Friedrich-Loeffler-Institut · DEBoehringer Ingelheim (Germany) · DEUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary dysfunction was evaluated in pigs infected with porcine reproductive and respiratory syndrome virus (PRRSV, isolate VR-2332) and compared to clinical and pathological findings. Infected pigs developed fever, reduced appetite, respiratory distress and dullness at 9 days post-inoculation (dpi). Non-invasive pulmonary function tests using impulse oscillometry and rebreathing of test gases (He, CO) revealed peripheral airway obstruction, reduced lung compliance and reduced lung CO-transfer factor. PRRSV-induced pulmonary dysfunction was most marked at 9-18 dpi and was accompanied by a significantly increased respiratory rate and decreased tidal volume. Expiration was affected more than inspiration. On histopathological examination, multifocal areas of interstitial pneumonia (more severe and extensive at 10 dpi than 21 dpi) were identified as a possible structural basis for reduced lung compliance and gas exchange disturbances.

Indexed as

AnimalsEnzyme-Linked Immunosorbent AssayFemaleImmunohistochemistryMalePolymerase Chain ReactionPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusRespiratory Function TestsSwine

Identifiers

PMID20089425
PMCPMC7128265
OpenAlexW2170202273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.