ArticlePLoS biology2010
The compartmentalized bacteria of the planctomycetes-verrucomicrobia-chlamydiae superphylum have membrane coat-like proteins.
Article in PLoS biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 76 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
76 citing papers in PubMed, 147 citations in OpenAlex.
- Microbe Profile:Microbiology (Reading, England) · 2026Review
- Plasma membrane invaginations and their diverse cellular functions.BMC biology · 2026Review
- A century of research on the Planctomycetota bacterial phylum, previously known as Planctomycetes.FEMS microbiology reviews · 2025Review
- Quest for Orthologs in the Era of Biodiversity Genomics.Genome biology and evolution · 2024Review
- The Last Universal Common Ancestor of Ribosome-Encoding Organisms: Portrait of LUCA.Journal of molecular evolution · 2024Review
- Clustering protein functional families at large scale with hierarchical approaches.Protein science : a publication of the Protein Society · 2024Article
- Article
- Stieleria tagensis sp. nov., a novel member of the phylum Planctomycetota isolated from Tagus River in Portugal.Antonie van Leeuwenhoek · 2023Article
- Reconciling Asgardarchaeota Phylogenetic Proximity to Eukaryotes and Planctomycetes Cellular Features in the Evolution of Life.Molecular biology and evolution · 2021Article
- Single Cell Cryo-Soft X-ray Tomography Shows That EachLife (Basel, Switzerland) · 2021Article
- Multidomain ribosomal protein trees and the planctobacterial origin of neomura (eukaryotes, archaebacteria).Protoplasma · 2020Review
- Full-repertoire comparison of the microscopic objects composing the human gut microbiome with sequenced and cultured communities.Journal of microbiology (Seoul, Korea) · 2020Article
- Phagocytosis-like cell engulfment by a planctomycete bacterium.Nature communications · 2019Article
- Extracellular membrane vesicles in the three domains of life and beyond.FEMS microbiology reviews · 2019Review
- Commentary: Manifold Routes to a Nucleus.Frontiers in microbiology · 2019Article
- The Paradigms They Are a-Changin': past, present and future of PVC bacteria research.Antonie van Leeuwenhoek · 2018Review
- Correction: The Compartmentalized Bacteria of the Planctomycetes-Verrucomicrobia-Chlamydiae Superphylum Have Membrane Coat-Like Proteins.PLoS biology · 2018Article
- PVCbase: an integrated web resource for the PVC bacterial proteomes.Database : the journal of biological databases and curation · 2018Article
- A plasmid from an Antarctic haloarchaeon uses specialized membrane vesicles to disseminate and infect plasmid-free cells.Nature microbiology · 2017Article
- Uncharacterized Bacterial Structures Revealed by Electron Cryotomography.Journal of bacteriology · 2017Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
The development of the endomembrane system was a major step in eukaryotic evolution. Membrane coats, which exhibit a unique arrangement of beta-propeller and alpha-helical repeat domains, play key roles in shaping eukaryotic membranes. Such proteins are likely to have been present in the ancestral eukaryote but cannot be detected in prokaryotes using sequence-only searches. We have used a structure-based detection protocol to search all proteomes for proteins with this domain architecture. Apart from the eukaryotes, we identified this protein architecture only in the Planctomycetes-Verrucomicrobia-Chlamydiae (PVC) bacterial superphylum, many members of which share a compartmentalized cell plan. We determined that one such protein is partly localized at the membranes of vesicles formed inside the cells in the planctomycete Gemmata obscuriglobus. Our results demonstrate similarities between bacterial and eukaryotic compartmentalization machinery, suggesting that the bacterial PVC superphylum contributed significantly to eukaryogenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.