ArticleAntimicrobial agents and chemotherapy2010
Pharmacokinetics of liposomal amphotericin B in pleural fluid.
Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Characteristics of pulmonary mucormycosis and predictive risk factors for the outcome.Infection · 2018Pooled it
- Post-Lobectomy Pleural Aspergillosis with Bronchopleural Fistula in a Patient with Metastatic Synovial Sarcoma of the Lung: A Case Report.Journal of clinical medicine · 2026Article
- SARS-CoV-2 infection enhancement by amphotericin B: implications for disease management.Journal of virology · 2025Article
- Disseminated fusariosis after allogenic hematopoietic stem cell transplantation: case report.Infection · 2025Article
- Application and evaluation of topical amphotericin B for the treatment of respiratory fungal infections.BMC infectious diseases · 2024Article
- The outcomes of thoracoscopic decortication between fungal empyema and bacterial empyema.BMC infectious diseases · 2023Article
- A Case Report ofFrontiers in public health · 2022Article
- Systemic and Target-Site Pharmacokinetics of Antiparasitic Agents.Clinical pharmacokinetics · 2020Review
- Review
- Tissue penetration of antifungal agents.Clinical microbiology reviews · 2014Review
- Pharmacokinetics of anidulafungin in pleural fluid during the treatment of a patient with Candida empyema.Antimicrobial agents and chemotherapy · 2011Article
- Refractory bronchovascular pleuropulmonary mucormycosis: Case report and difficulties in management.Lung India : official organ of Indian Chest SocietyArticle
- A 19-year-old woman with pleuritic chest pain.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicaleArticle
- Melanoma brain metastases: is it time to reassess the bias?Current problems in cancerArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 1 country.
Funding
Abstract
We report the penetration of liposomal amphotericin B into the pleural fluid of a patient with pulmonary zygomycosis and empyema. The ratio of area under the concentration-versus-time curve in pleural fluid (AUC(pleural fluid)) to that in serum (AUC(serum)) for liposomal amphotericin B over 24 h was 9.4%, with pleural fluid concentrations of 2.12 to 4.91 microg/ml. Given the relatively low level of intrapleural penetration of liposomal amphotericin B, chest tube drainage may be warranted for successful treatment of zygomycotic empyema.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.