Ductal origin hypothesis of pancreatic regeneration under attack.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

42 citing papers in PubMed.

1. β-Cell Regeneration Is Driven by Pancreatic Plasticity.Advances in anatomy, embryology, and cell biology · 2024
   Review
2. Insulin-positive ductal cells do not migrate into preexisting islets during pregnancy.Experimental & molecular medicine · 2021
   Article
3. PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice.The Journal of clinical investigation · 2019
   Article
4. In the setting of β-cell stress, the pancreatic duct gland transcriptome shows characteristics of an activated regenerative response.American journal of physiology. Gastrointestinal and liver physiology · 2018
   Article
5. Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic.Stem cell reports · 2018
   Article
6. Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes.Cell stem cell · 2018
   Article
7. Emerging Roles for Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) in Pancreatic Beta Cells and Diabetes.Frontiers in physiology · 2018
   Review
8. Increased Proliferation of the Pancreatic Duct Gland Compartment in Type 1 Diabetes.The Journal of clinical endocrinology and metabolism · 2017
   Article
9. Progress and challenges in macroencapsulation approaches for type 1 diabetes (T1D) treatment: Cells, biomaterials, and devices.Biotechnology and bioengineering · 2016
   Review
10. Centroacinar cells: At the center of pancreas regeneration.Developmental biology · 2016
    Review
11. Stem cells versus plasticity in liver and pancreas regeneration.Nature cell biology · 2016
    Review
12. Stem cells to replace or regenerate the diabetic pancreas: Huge potential & existing hurdles.The Indian journal of medical research · 2016
    Review
13. Beta Cell Regeneration in Adult Mice: Controversy Over the Involvement of Stem Cells.Current stem cell research & therapy · 2016
    Review
14. Intraislet Pancreatic Ducts Can Give Rise to Insulin-Positive Cells.Endocrinology · 2016
    Article
15. Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation.Stem cells translational medicine · 2015
    Review
16. Very small embryonic-like stem cells are involved in pancreatic regeneration and their dysfunction with age may lead to diabetes and cancer.Stem cell research & therapy · 2015
    Review
17. Compensatory Response by Late Embryonic Tubular Epithelium to the Reduction in Pancreatic Progenitors.PloS one · 2015
    Article
18. Islet cell plasticity and regeneration.Molecular metabolism · 2014
    Review
19. Microenvironmental stimuli for proliferation of functional islet β-cells.Cell & bioscience · 2014
    Article
20. Concise review: clinical programs of stem cell therapies for liver and pancreas.Stem cells (Dayton, Ohio) · 2013
    Review

Corrections and comments

• Erratum issued

Authors and funding

3 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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