ArticleCancer causes & control : CCC2010
Lifetime exposure to arsenic in drinking water and bladder cancer: a population-based case-control study in Michigan, USA.
Article in Cancer causes & control : CCC, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 5 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 5 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Cigarette smoking and risk of bladder cancer: a dose-response meta-analysis.International urology and nephrology · 2022Pooled it
- Bayesian hierarchical dose-response meta-analysis of epidemiological studies: Modeling and target population prediction methods.Environment international · 2020Pooled it
- Use of study-specific MOE-like estimates to prioritize health effects from chemical exposure for analysis in human health assessments.Environment international · 2020Pooled it
- Systematic dose-response of environmental epidemiologic studies: Dose and response pre-analysis.Environment international · 2020Pooled it
- Arsenic in drinking water and urinary tract cancers: a systematic review of 30 years of epidemiological evidence.Environmental health : a global access science source · 2014Pooled it
- Integrated Deterministic and Probabilistic Health Risk Assessment of Potentially Toxic Elements in Pistachio Cultivars from Southeast of Iran.Biological trace element research · 2026Article
- Update of the risk assessment of inorganic arsenic in food.EFSA journal. European Food Safety Authority · 2024Article
- Low-to-Moderate Arsenic Exposure and Urothelial Tract Cancers with a Long Latent Period of Follow-Up in an Arseniasis Area.Journal of epidemiology and global health · 2023Article
- Utilizing residential histories to assess environmental exposure and socioeconomic status over the life course among mesothelioma patients.Journal of thoracic disease · 2023Article
- Ethnic enclaves and colon cancer stage at diagnosis among New Jersey Hispanics.Social science & medicine (1982) · 2023Article
- Trace elements in Foodstuffs from the Mediterranean Basin-Occurrence, Risk Assessment, Regulations, and Prevention strategies: A review.Biological trace element research · 2023Review
- Review
- Utilizing Residential History to Examine Heterogeneous Exposure Trajectories: A Latent Class Mixed Modeling Approach Applied to Mesothelioma Patients.Journal of registry management · 2023Article
- Estimating mixture effects and cumulative spatial risk over time simultaneously using a Bayesian index low-rank kriging multiple membership model.Statistics in medicine · 2022Article
- Ambient UVR and Environmental Arsenic Exposure in Relation to Cutaneous Melanoma in Iowa.International journal of environmental research and public health · 2022Article
- Aggregated cumulative county arsenic in drinking water and associations with bladder, colorectal, and kidney cancers, accounting for population served.Journal of exposure science & environmental epidemiology · 2021Article
- Toxic Metal Implications on Agricultural Soils, Plants, Animals, Aquatic life and Human Health.International journal of environmental research and public health · 2020Review
- Urinary metals and metal mixtures in midlife women: The Study of Women's Health Across the Nation (SWAN).International journal of hygiene and environmental health · 2019Article
- Minerals from Macroalgae Origin: Health Benefits and Risks for Consumers.Marine drugs · 2018Review
- Lead facilitates foci formation in a Balb/c-3T3 two-step cell transformation model: role of Ape1 function.Environmental science and pollution research international · 2018Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveArsenic in drinking water has been linked with the risk of urinary bladder cancer, but the dose-response relationships for arsenic exposures below 100 microg/L remain equivocal. We conducted a population-based case-control study in southeastern Michigan, USA, where approximately 230,000 people were exposed to arsenic concentrations between 10 and 100 microg/L.
methodsThis study included 411 bladder cancer cases diagnosed between 2000 and 2004, and 566 controls recruited during the same period. Individual lifetime exposure profiles were reconstructed, and residential water source histories, water consumption practices, and water arsenic measurements or modeled estimates were determined at all residences. Arsenic exposure was estimated for 99% of participants' person-years.
resultsOverall, an increase in bladder cancer risk was not found for time-weighted average lifetime arsenic exposure >10 microg/L when compared with a reference group exposed to <1 microg/L (odds ratio (OR) = 1.10; 95% confidence interval (CI): 0.65, 1.86). Among ever-smokers, risks from arsenic exposure >10 microg/L were similarly not elevated when compared to the reference group (OR = 0.94; 95% CI: 0.50, 1.78).
conclusionsWe did not find persuasive evidence of an association between low-level arsenic exposure and bladder cancer. Selecting the appropriate exposure metric needs to be thoughtfully considered when investigating risk from low-level arsenic exposure.
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Registered trials
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