ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2010
Genetic analysis of disease susceptibility contributed by the compatible Tsn1-SnToxA and Snn1-SnTox1 interactions in the wheat-Stagonospora nodorum pathosystem.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 36 citations in OpenAlex.
- A fungal nuclease effector subverts the chloroplast genome and triggers cell death to promote infection.Nature plants · 2026Article
- Variability in an effector gene promoter of a necrotrophic fungal pathogen dictates epistasis and effector-triggered susceptibility in wheat.PLoS pathogens · 2022Article
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- Reactive Oxygen Species in Host Plant Are Required for an Early Defense Response against Attack ofPlants (Basel, Switzerland) · 2021Article
- Genetic mapping using a wheat multi-founder population reveals a locus on chromosome 2A controlling resistance to both leaf and glume blotch caused by the necrotrophic fungal pathogen Parastagonospora nodorum.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Article
- Role of Effector-Sensitivity Gene Interactions and Durability of Quantitative Resistance to Septoria Nodorum Blotch in Eastern U.S. Wheat.Frontiers in plant science · 2020Article
- Genetics of Variable Disease Expression Conferred by Inverse Gene-For-Gene Interactions in the Wheat-Plant physiology · 2019Article
- Assessing European Wheat Sensitivities toFrontiers in plant science · 2018Article
- New Insights into the Roles of Host Gene-Necrotrophic Effector Interactions in Governing Susceptibility of Durum Wheat to Tan Spot and Septoria nodorum Blotch.G3 (Bethesda, Md.) · 2016Article
- The hijacking of a receptor kinase-driven pathway by a wheat fungal pathogen leads to disease.Science advances · 2016Article
- Proteome changes induced by Pyrenophora tritici-repentis ToxA in both insensitive and sensitive wheat indicate senescence-like signaling.Proteome science · 2015Article
- Functional redundancy of necrotrophic effectors - consequences for exploitation for breeding.Frontiers in plant science · 2015Article
- Resequencing and comparative genomics of Stagonospora nodorum: sectional gene absence and effector discovery.G3 (Bethesda, Md.) · 2013Article
- SnTox5-Snn5: a novel Stagonospora nodorum effector-wheat gene interaction and its relationship with the SnToxA-Tsn1 and SnTox3-Snn3-B1 interactions.Molecular plant pathology · 2012Article
- New broad-spectrum resistance to septoria tritici blotch derived from synthetic hexaploid wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
- Genetic analysis of resistance to septoria tritici blotch in the French winter wheat cultivars Balance and Apache.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011Article
- Rice xa13 recessive resistance to bacterial blight is defeated by induction of the disease susceptibility gene Os-11N3.The Plant cell · 2010Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stagonospora nodorum is a foliar pathogen of wheat that produces several host-selective toxins (HSTs) and causes the disease Stagonospora nodorum blotch (SNB). The wheat genes Snn1 and Tsn1 confer sensitivity to the HSTs SnTox1 and SnToxA, respectively. The objectives of this study were to dissect, quantify, and compare the effects of compatible Snn1-SnTox1 and Tsn1-SnToxA interactions on susceptibility in the wheat-S. nodorum pathosystem. Inoculation of a wheat doubled haploid population that segregates for both Snn1 and Tsn1 with an S. nodorum isolate that produces both SnTox1 and SnToxA indicated that both interactions were strongly associated with SNB susceptibility. The Snn1-SnTox1 and Tsn1-SnToxA interactions explained 22 and 28% of the variation in disease, respectively, and together they explained 48% indicating that their effects are largely additive. The Snn1-SnTox1 interaction accounted for 50% of the variation when the population was inoculated with an S. nodorum strain where the SnToxA gene had been mutated, eliminating the Tsn1-SnToxA interaction. These results support the theory that the wheat-S. nodorum pathosystem is largely based on multiple host-toxin interactions that follow an inverse gene-for-gene scenario at the host-toxin interface, but disease exhibits quantitative variation due to the mainly additive nature of compatible interactions. The elimination of either Snn1 or Tsn1 toxin sensitivity alleles resulted in decreased susceptibility, but the elimination of both interactions was required to obtain high levels of resistance. We propose the use of molecular markers to select against Snn1, Tsn1, and other toxin sensitivity alleles to develop wheat varieties with high levels of SNB resistance.
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