ArticleInternal and emergency medicine2010
A comparison amongst three rapid urease tests to diagnose Helicobacter pylori infection in 375 consecutive dyspeptic.
Article in Internal and emergency medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-invasive diagnostic tests for Helicobacter pylori infection.The Cochrane database of systematic reviews · 2018Pooled it
- A prospective study for evaluating the effect of gastric targeted biopsy sampling with I-scan optical enhancement on the diagnostic yield of CLOtest forHealth science reports · 2022Article
- Colonization ofJGH open : an open access journal of gastroenterology and hepatology · 2018Article
- A Novel Stool PCR Test for Helicobacter pylori May Predict Clarithromycin Resistance and Eradication of Infection at a High Rate.Journal of clinical microbiology · 2017Article
- A multicenter prospective study on the diagnostic performance of a new liquid rapid urease test for the diagnosis ofGut pathogens · 2017Article
- Real-time diagnosis of H. pylori infection during endoscopy: Accuracy of an innovative tool (EndoFaster).United European gastroenterology journal · 2016Article
- Diagnostic Methods of Helicobacter pylori Infection for Epidemiological Studies: Critical Importance of Indirect Test Validation.BioMed research international · 2016Review
- Liver involvement in hereditary hemorrhagic telangiectasia: can breath test unmask impaired hepatic first-pass effect?Internal and emergency medicine · 2012Article
- Rapid urease test for H. pylori diagnosis: pros and cons.Internal and emergency medicine · 2010Article
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8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid diagnostic tools for Helicobacter pylori are important in endoscopy. To assess the accuracy of a new 5-min rapid urease test (UFT300, ABS Cernusco, sul Naviglio, Italy) compared with the 1-h Pyloritek (Serim Laboratories, Elkhart, IN) and the 24-h CLO test (Kimberly-Clark Ballard Medical Products, Roswell, GA), consecutive dyspeptic patients referred to our unit for endoscopy were prospectively studied. All patients underwent a 13C-urea-breath test, histology and the UFT300 (ABS; Cernusco, sul Naviglio, Italy). Two additional rapid urease tests were performed. Patients were deemed infected when both 13C-UBT and histology were positive. Rapid urease tests were read at 1, 5, and 60 min, respectively. Of the 375 enrolled patients, 45.3% were infected with H. pylori. The sensitivity of the new 5-min rapid urease test 300 was 90.3, 94.5, and 96.2% at 1, 5, and 60 min, respectively (specificity 100%). The Pyloritek and the new 5-min rapid urease test were comparable, but the CLO test was not reliable at 5 and 60 min. In conclusion, the new 5-min rapid urease test is comparable to the Pyloritek test, but the CLO test is significantly less sensitive at early time points. Reading the test results at 1 min may increase false-negative results with decreasing sensitivity.
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