Evidence map›Paper›PMID 20082061›Full record

ReviewDer Anaesthesist2010

[Update: invasive fungal infections: Diagnosis and treatment in surgical intensive care medicine].

C Lichtenstern, S Swoboda, M Hirschburger, E Domann, T Hoppe-Tichy, M Winkler, C Lass-Flörl, M A Weigand

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Anaesthesist, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

C LichtensternKlinik für Anaesthesiologie und Operative Intensivmedizin, Universitätsklinikum Giessen und Marburg, Standort Giessen, Germany. christoph.lichtenstern@chiru.med.uni-giessen.de
S Swoboda
M Hirschburger
E Domann
T Hoppe-Tichy
M Winkler
C Lass-Flörl
M A Weigand
Universitätsklinikum Gießen und Marburg · DEUniversity Hospital Heidelberg · DEInnsbruck Medical University · ATMedizinische Hochschule Hannover · DEUniversity of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal infections are of great relevance in surgical intensive care and Candida species represent the predominant part of fungal pathogens. Invasive aspergillosis is also relevant especially in patients with chronic pulmonary diseases. It is crucial for therapy success to begin adequate antifungal treatment at an early stage of the disease. Risk stratification of individual patient symptoms is essential for therapy timing. In case of suspected or proven candida infection, fluconazole is the agent of choice when the patient is clinically stable and no azoles have been administrated in advance and the local epidemiology makes azol resistance unlikely. For clinically instable patients with organ dysfunction the echinocandins serve as primary therapy because of their broad spectrum and reasonable safety profile. Due to a relevant proportion of azole resistant Candida species, susceptibility testing should be done routinely. Depending on the species detected de-escalating to an azole is feasible if organ dysfunctions have resolved. An invasive aspergillosis is primarily treated with voriconazole.

Indexed as

Critical CareAdjuvants, ImmunologicAntifungal AgentsAzolesbeta-GlucansCandidiasisCryptococcosisEchinocandinsGalactoseHumansMannansMucusMycosesPolyenesReverse Transcriptase Polymerase Chain ReactionRisk AssessmentAdjuvants, ImmunologicAntifungal AgentsAzolesbeta-1,3-glucanbeta-GlucansEchinocandinsgalactomannanGalactoseMannansPolyenes

Identifiers

PMID20082061
OpenAlexW1480237647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.