Evidence map›Paper›PMID 20081007›Full record

ArticleApplied and environmental microbiology2010

Selection from industrial lager yeast strains of variants with improved fermentation performance in very-high-gravity worts.

Anne Huuskonen, Tuomas Markkula, Virve Vidgren, Luis Lima, Linda Mulder, Wim Geurts, Michael Walsh, John Londesborough

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
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  10. Use of IndigenousFrontiers in microbiology · 2018
    Article
  11. Article
  12. Article
  13. Novel brewing yeast hybrids: creation and application.Applied microbiology and biotechnology · 2017
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Anne HuuskonenVTT Technical Research Centre of Finland, P.O. Box 1000, FIN-02044 VTT, Finland.
Tuomas Markkula
Virve Vidgren
Luis Lima
Linda Mulder
Wim Geurts
Michael Walsh
John Londesborough
VTT Technical Research Centre of Finland · FIHeineken (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are economic and other advantages if the fermentable sugar concentration in industrial brewery fermentations can be increased from that of currently used high-gravity (ca. 14 to 17 degrees P [degrees Plato]) worts into the very-high-gravity (VHG; 18 to 25 degrees P) range. Many industrial strains of brewer's yeast perform poorly in VHG worts, exhibiting decreased growth, slow and incomplete fermentations, and low viability of the yeast cropped for recycling into subsequent fermentations. A new and efficient method for selecting variant cells with improved performance in VHG worts is described. In this new method, mutagenized industrial yeast was put through a VHG wort fermentation and then incubated anaerobically in the resulting beer while maintaining the alpha-glucoside concentration at about 10 to 20 g.liter(-1) by slowly feeding the yeast maltose or maltotriose until most of the cells had died. When survival rates fell to 1 to 10 cells per 10(6) original cells, a high proportion (up to 30%) of survivors fermented VHG worts 10 to 30% faster and more completely (residual sugars lower by 2 to 8 g.liter(-1)) than the parent strains, but the sedimentation behavior and profiles of yeast-derived flavor compounds of the survivors were similar to those of the parent strains.

Indexed as

Alcoholic BeveragesCarbohydrate MetabolismFermentationGenetic VariationMicrobial ViabilityMutagenesisSaccharomyces cerevisiaeSelection, Genetic

Identifiers

PMID20081007
PMCPMC2832358
OpenAlexW2162175021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.