Evidence map›Paper›PMID 20080892›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2010

In vivo imaging of RNA interference.

Hao Hong, Yin Zhang, Weibo Cai

Abstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Precision Oncology: Advances in Drug Delivery and Imaging.Recent advances in drug delivery and formulation · 2025
    Review
  2. Article
  3. Article
  4. Imaging-guided delivery of RNAi for anticancer treatment.Advanced drug delivery reviews · 2016
    Review
  5. Review
  6. Technologies for investigating the physiological barriers to efficient lipid nanoparticle-siRNA delivery.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2013
    Review
  7. Multimodality imaging of RNA interference.Current medicinal chemistry · 2013
    Review
  8. Near-infrared molecular probes for in vivo imaging.Current protocols in cytometry · 2012
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Tumor-targeted drug delivery with aptamers.Current medicinal chemistry · 2011
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hao HongDepartments of Radiology and Medical Physics and University of Wisconsin Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin 53705, USA.
Yin Zhang
Weibo Cai

Funding

INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
NCRR NIH HHS 1UL1RR025011NCRR NIH HHS UL1 RR025011
6 · The paper itself

Abstract

RNA interference (RNAi), an effective technique for regulating or silencing specific genes, can be applied to treat various diseases. Multiple clinical trials using RNAi are ongoing, and molecular imaging can serve as a powerful tool in RNAi-based therapies. This brief review will highlight the current progress on in vivo imaging of RNAi delivery and silencing effects. Incorporation of suitable molecular imaging techniques into future RNAi-based clinical trials will provide more pieces of the puzzle, thus facilitating the transformation of RNAi into a powerful therapeutic modality in the clinic.

Indexed as

RNA InterferenceAnimalsGene SilencingHumansLuminescent MeasurementsMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMicroscopy, FluorescenceMolecular ImagingPositron-Emission TomographyQuantum DotsRNA, Small InterferingTomography, Emission-Computed, Single-PhotonRNA, Small Interfering

Identifiers

PMID20080892
PMCPMC2832477

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.