ArticleMolecular biology and evolution2010
Sperm proteomics reveals intensified selection on mouse sperm membrane and acrosome genes.
Article in Molecular biology and evolution, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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Who cites it
60 citing papers in PubMed.
- Determining gene specificity from multivariate single-cell RNA sequencing data.bioRxiv : the preprint server for biology · 2025Article
- Non-human primates as a translational model for the study of male reproductive health.Nature reviews. Urology · 2025Review
- A comparison of spermatogenesis between flies and men-conserved processes of male gamete production.Human reproduction update · 2025Review
- Haplodiploidy accelerates mitogenome evolution in insects.Proceedings. Biological sciences · 2025Article
- Mating system variation and gene expression in the male reproductive tract of Peromyscus mice.Molecular ecology · 2025Article
- Sharp decline in male fertility in F2 hybrids of the female-heterogametic silk moth Bombyx.Genetics · 2024Article
- Leucine aminopeptidase1 controls egg deposition and hatchability in male Aedes aegypti mosquitoes.Nature communications · 2024Article
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- Candidate genes for infertility: an in-silico study based on cytogenetic analysis.BMC medical genomics · 2022Article
- Sperm acquire epididymis-derived proteins through epididymosomes.Human reproduction (Oxford, England) · 2022Article
- Evolutionary, proteomic, and experimental investigations suggest the extracellular matrix of cumulus cells mediates fertilization outcomes†.Biology of reproduction · 2021Article
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- RNA-Seq of three free-living flatworm species suggests rapid evolution of reproduction-related genes.BMC genomics · 2020Article
- Evolutionary analysis of genes coding for Cysteine-RIch Secretory Proteins (CRISPs) in mammals.BMC evolutionary biology · 2020Article
- Integrated Analyses of Phenotype and Quantitative Proteome of CMTM4 Deficient Mice Reveal Its Association with Male Fertility.Molecular & cellular proteomics : MCP · 2019Article
- RNA-seq coupled to proteomic analysis reveals high sperm proteome variation between two closely related marine mussel species.Journal of proteomics · 2019Article
- Sperm-Leucylaminopeptidases are required for male fertility as structural components of mitochondrial paracrystalline material in Drosophila melanogaster sperm.PLoS genetics · 2019Article
- Article
- Differential motility parameters and identification of proteomic profiles of human sperm cryopreserved with cryostraw and cryovial.Clinical proteomics · 2019Article
- Positive Selection in the Evolution of Mammalian CRISPs.Journal of molecular evolution · 2018Article
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5 authors.
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Abstract
Spermatozoa are a focal point for the impact of sexual selection due to sperm competition and sperm-female interactions in a wide range of sexually reproducing organisms. In-depth molecular investigation of the ramifications of these selective regimes has been limited due to a lack of information concerning the molecular composition of sperm. In this study, we utilize three previously published proteomic data sets in conjunction with our whole mouse sperm proteomic analysis to delineate cellular regions of sperm most impacted by positive selection. Interspecific analysis reveals robust evolutionary acceleration of sperm cell membrane genes (which include genes encoding acrosomal and sperm cell surface proteins) relative to other sperm genes, and evidence for positive selection in approximately 22% of sperm cell membrane components was obtained using maximum likelihood models. The selective forces driving the accelerated evolution of these membrane proteins may occur at a number of locations during sperm development, maturation, and transit through the female reproductive tract where the sperm cell membrane and eventually the acrosome are exposed to the extracellular milieu and available for direct cell-cell interactions.
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