ArticleProceedings of the National Academy of Sciences of the United States of America2010
Engineering the cell wall by reducing de-methyl-esterified homogalacturonan improves saccharification of plant tissues for bioconversion.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
91 citing papers in PubMed, 210 citations in OpenAlex.
- Pectin under stress: Pectin methylesterases at the core of cell wall remodeling, integrity sensing, and signaling in plants.Plant communications · 2026Review
- Functional architecture and cell wall composition of peltate scales involved in leaf water absorption.Frontiers in plant science · 2026Article
- Ectopic expression of pectate lyaseiScience · 2025Article
- Cell wall remodeling and polarized light analysis reveal ecotype-specific strategies in Salicornia europaea L. with biotechnological applications.Scientific reports · 2025Article
- Anaerobic fungi: effective warriors in lignocellulosic biomass degradation and fermentation.FEMS microbiology ecology · 2025Review
- Dual role of pectin methyl esterase activity in the regulation of plant cell wall biophysical properties.Frontiers in plant science · 2025Article
- Pull the fuzes: Processing protein precursors to generate apoplastic danger signals for triggering plant immunity.Plant communications · 2024Review
- Epigenetic weapons of plants against fungal pathogens.BMC plant biology · 2024Review
- Endophytic non-pathogenicFrontiers in plant science · 2024Article
- Insights into pectinCell surface (Amsterdam, Netherlands) · 2023Review
- Multi-Step Enzymatic Production and Purification of 2-Keto-3-Deoxy-Galactonate from Red-Macroalgae-Derived Agarose.Marine drugs · 2022Article
- The Plant Invertase/Pectin Methylesterase Inhibitor Superfamily.Frontiers in plant science · 2022Review
- Tailoring renewable materials via plant biotechnology.Biotechnology for biofuels · 2021Review
- Diatom fucan polysaccharide precipitates carbon during algal blooms.Nature communications · 2021Article
- Host Cell Wall Damage during Pathogen Infection: Mechanisms of Perception and Role in Plant-Pathogen Interactions.Plants (Basel, Switzerland) · 2021Review
- Impaired Cuticle Functionality and Robust Resistance toFrontiers in plant science · 2021Article
- Expression of a Hyperthermophilic Cellobiohydrolase in TransgenicPlants (Basel, Switzerland) · 2020Article
- Comparative phenotypic and transcriptomic analysis of Victoria and flame seedless grape cultivars during berry ripening.FEBS open bio · 2020Article
- Post-Synthetic Reduction of Pectin Methylesterification Causes Morphological Abnormalities and Alterations to Stress Response inPlants (Basel, Switzerland) · 2020Article
- The Homogalacturonan Deconstruction System of Paenibacillus amylolyticus 27C64 Requires No Extracellular Pectin Methylesterase and Has Significant Industrial Potential.Applied and environmental microbiology · 2020Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Plant cell walls represent an abundant, renewable source of biofuel and other useful products. The major bottleneck for the industrial scale-up of their conversion to simple sugars (saccharification), to be subsequently converted by microorganisms into ethanol or other products, is their recalcitrance to enzymatic saccharification. We investigated whether the structure of pectin that embeds the cellulose-hemicellulose network affects the exposure of cellulose to enzymes and consequently the process of saccharification. Reduction of de-methyl-esterified homogalacturonan (HGA) in Arabidopsis plants through the expression of a fungal polygalacturonase (PG) or an inhibitor of pectin methylesterase (PMEI) increased the efficiency of enzymatic saccharification. The improved enzymatic saccharification efficiency observed in transformed plants could also reduce the need for acid pretreatment. Similar results were obtained in PG-expressing tobacco plants and in PMEI-expressing wheat plants, indicating that reduction of de-methyl-esterified HGA may be used in crop species to facilitate the process of biomass saccharification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.