ReviewSeminars in cell & developmental biology2010
Computational methods to identify miRNA targets.
Review in Seminars in cell & developmental biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed.
- MicroRNA-phytochemical interactome targeting thioredoxin-interacting protein: a narrative review at the nexus of RNA therapeutics, cancer biology, and metabolic regulation.Frontiers in oncology · 2026Review
- miRNAProtPred: computational prediction of human miRNA binding based on seed complementarity and thermodynamic stability.Frontiers in genetics · 2026Article
- Exploring the therapeutic potential of microRNAs: targeted gene regulation strategies for enhanced cancer therapy.Journal, genetic engineering & biotechnology · 2025Review
- Comparative and Functional Analysis of Exosomal microRNAs During Semelparous Reproduction in Ayu Fish (Journal of extracellular biology · 2025Article
- AAAGUGC Seed-Containing miRNAs: Master Regulators of Cancer Pathways and Therapeutic Resistance.MicroRNA (Shariqah, United Arab Emirates) · 2025Review
- A Thorough Navigation of miRNA's Blueprint in Crafting Cardiovascular Fate.Health science reports · 2024Article
- Prediction methods for microRNA targets in bilaterian animals: Toward a better understanding by biologists.Computational and structural biotechnology journal · 2021Review
- Review
- Review
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- Identification of miRNAs Potentially Involved in Bronchiolitis Obliterans Syndrome: A Computational Study.PloS one · 2016Article
- Down-regulation of miR-135b in colon adenocarcinoma induced by a TGF-β receptor I kinase inhibitor (SD-208).Iranian journal of basic medical sciences · 2015Article
- microRNAs function in CD8+T cell biology.Journal of leukocyte biology · 2015Review
- Computational developments in microRNA-regulated protein-protein interactions.BMC systems biology · 2014Review
- Integrative identification of deregulated miRNA/TF-mediated gene regulatory loops and networks in prostate cancer.PloS one · 2014Article
- Macros in microRNA target identification: a comparative analysis of in silico, in vitro, and in vivo approaches to microRNA target identification.RNA biology · 2014Review
- The imprinted H19 lncRNA antagonizes let-7 microRNAs.Molecular cell · 2013Article
- BayMiR: inferring evidence for endogenous miRNA-induced gene repression from mRNA expression profiles.BMC genomics · 2013Article
- Advances in the techniques for the prediction of microRNA targets.International journal of molecular sciences · 2013Review
- Searching the coding region for microRNA targets.RNA (New York, N.Y.) · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
MicroRNAs (miRNAs) are short RNA molecules that regulate the post-transcriptional expression of their target genes. This regulation may take the form of stable translational or degradation of the target transcript, although the mechanisms governing the outcome of miRNA-mediated regulation remain largely unknown. While it is becoming clear that miRNAs are core components of gene regulatory networks, elucidating precise roles for each miRNA within these networks will require an accurate means of identifying target genes and assessing the impact of miRNAs on individual targets. Numerous computational methods for predicting targets are currently available. These methods vary widely in their emphasis, accuracy, and ease of use for researchers. This review will focus on a comparison of the available computational methods in animals, with an emphasis on approaches that are informed by experimental analysis of microRNA:target complexes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.