ArticleMolecular plant pathology2010
Why Rice yellow mottle virus, a rapidly evolving RNA plant virus, is not efficient at breaking rymv1-2 resistance.
Article in Molecular plant pathology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Deciphering mixed infections by plant RNA virus and reconstructing complete genomes simultaneously present within-host.PloS one · 2025Article
- A meta-analysis highlights the idiosyncratic nature of tradeoffs in laboratory models of virus evolution.Virus evolution · 2024Article
- The proportion of resistant hosts in mixtures should be biased towards the resistance with the lowest breaking cost.PLoS computational biology · 2023Article
- Molecular Tools to Infer Resistance-Breaking Abilities of Rice Yellow Mottle Virus Isolates.Viruses · 2023Article
- Reversion of a resistance-breaking mutation shows reversion costs and high virus diversity at necrotic local lesions.Molecular plant pathology · 2023Article
- Dynamics of the rice yellow mottle disease in western Burkina Faso: Epidemic monitoring, spatio-temporal variation of viral diversity, and pathogenicity in a disease hotspot.Virus evolution · 2023Article
- Host mixtures for plant disease control: Benefits from pathogen selection and immune priming.Evolutionary applications · 2022Article
- Water deficit changes the relationships between epidemiological traits of Cauliflower mosaic virus across diverse Arabidopsis thaliana accessions.Scientific reports · 2021Article
- Analysis of Fitness Trade-Offs in the Host Range Expansion of an RNA Virus, Tobacco Mild Green Mosaic Virus.Journal of virology · 2018Article
- Engineered Functional Redundancy Relaxes Selective Constraints upon Endogenous Genes in Viral RNA Genomes.Genome biology and evolution · 2018Article
- Pleiotropic Effects of Resistance-Breaking Mutations on Particle Stability Provide Insight into Life History Evolution of a Plant RNA Virus.Journal of virology · 2017Article
- Virus-Bacteria Rice Co-Infection in Africa: Field Estimation, Reciprocal Effects, Molecular Mechanisms, and Evolutionary Implications.Frontiers in plant science · 2017Article
- Mutations That Determine Resistance Breaking in a Plant RNA Virus Have Pleiotropic Effects on Its Fitness That Depend on the Host Environment and on the Type, Single or Mixed, of Infection.Journal of virology · 2016Article
- P3N-PIPO, a Frameshift Product from the P3 Gene, Pleiotropically Determines the Virulence of Clover Yellow Vein Virus in both Resistant and Susceptible Peas.Journal of virology · 2016Article
- Human Management of a Wild Plant Modulates the Evolutionary Dynamics of a Gene Determining Recessive Resistance to Virus Infection.PLoS genetics · 2016Article
- Adaptation to resistant hosts increases fitness on susceptible hosts in the plant parasitic nematode Globodera pallida.Ecology and evolution · 2016Article
- Mutations inFrontiers in plant science · 2016Article
- Plant Translation Factors and Virus Resistance.Viruses · 2015Review
- Historical contingencies modulate the adaptability of Rice yellow mottle virus.PLoS pathogens · 2012Article
- A single-stranded conformational polymorphism (SSCP)-derived quantitative variable to monitor the virulence of a Barley yellow dwarf virus-PAV (BYDV-PAV) isolate during adaptation to the TC14 resistant wheat line.Molecular plant pathology · 2010Article
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4 authors.
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Abstract
Rice yellow mottle virus (RYMV) reaches a high virus content in rice, is genetically highly variable and evolves rapidly. Nevertheless, only a small proportion of isolates overcome rymv1-2 rice resistance by mutations in the VPg (viral protein genome-linked). The accumulation rates of wild-type (WT) and resistance-breaking (RB) genotypes of the E- and T-pathotypes of RYMV, with average and low virulence, respectively, were assessed. By quantitative reverse transcriptase-polymerase chain reaction, it was shown that: (i) in resistant plants, both WT genotypes reached a level of 10(5)-10(7) viral copies per milligram of fresh leaf; (ii) the accumulation of RB genotypes was variable, but was always much higher than the WT, with an RB/WT accumulation ratio of up to 10(6); (iii) in susceptible plants, the RB genotypes were counter-selected to a similar level. In competition experiments, there was a straightforward exclusion of WT by RB genotypes in resistant hosts. The mutation rate in VPg was more than 1 x 10(-3) mutations per site per year. Overall, a steady supply of highly adaptive RB genotypes was expected in resistant plants. However, the use of the few possible mutational pathways to virulence is tightly regulated by pathotype-specific genetic constraints: codon usage, mutational bias and sign epistasis. In addition, genetic drift may restrict the fixation of RB mutants. Altogether, both genetic and demographic constraints contribute to the low ability of RYMV to break rymv1-2 resistance.
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